Literature DB >> 6922089

Isolation and characterization of pneumolysin-negative mutants of Streptococcus pneumoniae.

M K Johnson, D Hamon, G K Drew.   

Abstract

Pneumolysin-negative mutants of Streptococcus pneumoniae were isolated after mutagenesis with ethyl methane sulfonate. Though totally devoid of pneumolysin, these strains produced alpha hemolysis on blood agar when incubated aerobically. It is concluded that the alpha hemolysis typical of pneumococci is unrelated to their pneumolysin content.

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Year:  1982        PMID: 6922089      PMCID: PMC347608          DOI: 10.1128/iai.37.2.837-839.1982

Source DB:  PubMed          Journal:  Infect Immun        ISSN: 0019-9567            Impact factor:   3.441


  2 in total

1.  Genetic transformation of Streptococcus pneumoniae by heterologous plasmid deoxyribonucleic acid.

Authors:  F Barany; A Tomasz
Journal:  J Bacteriol       Date:  1980-11       Impact factor: 3.490

2.  Properties of purified pneumococcal hemolysin.

Authors:  M K Johnson
Journal:  Infect Immun       Date:  1972-11       Impact factor: 3.441

  2 in total
  3 in total

1.  Production and purification of Streptococcus pneumoniae hemolysin (pneumolysin).

Authors:  K Kanclerski; R Möllby
Journal:  J Clin Microbiol       Date:  1987-02       Impact factor: 5.948

2.  Toxicity of pneumolysin to pulmonary endothelial cells in vitro.

Authors:  J B Rubins; P G Duane; D Charboneau; E N Janoff
Journal:  Infect Immun       Date:  1992-05       Impact factor: 3.441

3.  Identification of hydrogen peroxide as a Streptococcus pneumoniae toxin for rat alveolar epithelial cells.

Authors:  P G Duane; J B Rubins; H R Weisel; E N Janoff
Journal:  Infect Immun       Date:  1993-10       Impact factor: 3.441

  3 in total

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