Literature DB >> 6905674

The inability of superoxide dismutase to inhibit the depolymerization of hyaluronic acid by ferrous ions and ascorbate.

H Hofmann, O Schmut.   

Abstract

Superoxide radicals were investigated as to their capability of depolymerizing the hyaluronic acid of the bovine vitreous body. Using viscometry it was found that O2 radicals, generated by the hypoxanthine/xanthine oxidase method or the combination of NADH and phenazine methosulphate, degraded hyaluronic acid. This reaction was suppressed by superoxide dismutase, catalase, and peroxidase. In contrast, the depolymerization of hyaluronic acid by oxidation-reduction systems like ascorbic acid or ferrous ions was abolished by catalase and peroxidase while superoxide dismutase showed no effect.

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Year:  1980        PMID： 6905674     DOI： 10.1007/bf00414560

Source DB:  PubMed          Journal:  Albrecht Von Graefes Arch Klin Exp Ophthalmol        ISSN： 0065-6100


  14 in total

1.  Superoxide-dependent formation of hydroxyl radicals in the presence of iron salts. Its role in degradation of hyaluronic acid by a superoxide-generating system.

Authors:  B Halliwell
Journal:  FEBS Lett       Date:  1978-12-15       Impact factor: 4.124

2.  The occurrence of superoxide anion in the reaction of reduced phenazine methosulfate and molecular oxygen.

Authors:  M Nishikimi; N Appaji; K Yagi
Journal:  Biochem Biophys Res Commun       Date:  1972-01-31       Impact factor: 3.575

3.  Metal catalysis in the depolymerization of hyaluronic acid by autoxidants.

Authors:  M J Harris; A Herp; W Pigman
Journal:  J Am Chem Soc       Date:  1972-10-18       Impact factor: 15.419

4.  A consideration of the effects of added solutes on the activity of bovine superoxide dismutase.

Authors:  M E McAdam
Journal:  Biochem J       Date:  1977-03-01       Impact factor: 3.857

5.  Comparison of superoxide with other reducing agents in the biological production of hydroxyl radicals.

Authors:  C C Winterbourn
Journal:  Biochem J       Date:  1979-08-15       Impact factor: 3.857

6.  Superoxide dismutase: improved assays and an assay applicable to acrylamide gels.

Authors:  C Beauchamp; I Fridovich
Journal:  Anal Biochem       Date:  1971-11       Impact factor: 3.365

7.  A pulse-radiolysis study of the catalytic mechanism of the iron-containing superoxide dismutase from Photobacterium leiognathi.

Authors:  F Lavelle; M E McAdam; E M Fielden; P B Roberts
Journal:  Biochem J       Date:  1977-01-01       Impact factor: 3.857

8.  Studies on the generation of hydrogen peroxide during some non-enzymic reactions changing the hyaluronic acid molecule.

Authors:  O Schmut; H Hofmann
Journal:  Biochim Biophys Acta       Date:  1975-12-05

9.  Free radicals and inflammation: protection of synovial fluid by superoxide dismutase.

Authors:  J M McCord
Journal:  Science       Date:  1974-08-09       Impact factor: 47.728

10.  The mechanism of DNA strand breakage by vitamin C and superoxide and the protective roles of catalase and superoxide dismutase.

Authors:  A R Morgan; R L Cone; T M Elgert
Journal:  Nucleic Acids Res       Date:  1976-05       Impact factor: 16.971
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  2 in total

1.  Cigarette smoke degrades hyaluronic acid.

Authors:  C A McDevitt; G J Beck; M J Ciunga; J O'Brien
Journal:  Lung       Date:  1989       Impact factor: 2.584

Review 2.  Cigarette Smoke Particle-Induced Lung Injury and Iron Homeostasis.

Authors:  Andrew J Ghio; Elizabeth N Pavlisko; Victor L Roggli; Nevins W Todd; Rahul G Sangani
Journal:  Int J Chron Obstruct Pulmon Dis       Date:  2022-01-12
  2 in total

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