Literature DB >> 6903180

In vitro-activity of clavulanic acid and amoxicillin combined against amoxicillin-resistant bacteria.

G Peters, G Pulverer, M Neugebauer.   

Abstract

The ability of clavulanic acid to inactivate beta-lactamase was investigated using 47 amoxicillin-resistant bacteria. In the presence of 10 mg/l clavulanic acid most strains of staphylococci, Escherichia coli, Klebsiella and Proteus mirabilis became fully amoxicillin-sensitive. This effect of clavulanic acid was in most instances not observed with Serratia marcescens, Proteus inconstans, Pseudomonas aeruginosa, Enterobacter and indole-positive Proteus species.

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Year:  1980        PMID： 6903180     DOI： 10.1007/bf01641472

Source DB:  PubMed          Journal:  Infection        ISSN： 0300-8126            Impact factor:   3.553


  7 in total

1.  In vitro study of clavulanic acid in combination with penicillin, amoxycillin, and carbenicillin.

Authors:  R Wise; J M Andrews; K A Bedford
Journal:  Antimicrob Agents Chemother       Date:  1978-03       Impact factor: 5.191

2.  Naturally-occurring beta-lactamase inhibitors with antibacterial activity.

Authors:  A G Brown; D Butterworth; M Cole; G Hanscomb; J D Hood; C Reading; G N Rolinson
Journal:  J Antibiot (Tokyo)       Date:  1976-06       Impact factor: 2.649

3.  [Penicillinase-resistant penicillins and cephalosporin, an advance in the battle against resistant microbes].

Authors:  M H Richmond
Journal:  Dtsch Med Wochenschr       Date:  1977-08-26       Impact factor: 0.628

4.  Combined activitiy of clavulanic acid and ticarcillin against ticarcillin-resistant, gram-negative bacilli.

Authors:  J W Paisley; J A Washington
Journal:  Antimicrob Agents Chemother       Date:  1978-08       Impact factor: 5.191

Review 5.  The beta-lactamases of gram-negative bacteria and their role in resistance to beta-lactam antibiotics.

Authors:  R B Sykes; M Matthew
Journal:  J Antimicrob Chemother       Date:  1976-06       Impact factor: 5.790

6.  Clavulanic acid, a novel inhibitor of beta-lactamases.

Authors:  H C Neu; K P Fu
Journal:  Antimicrob Agents Chemother       Date:  1978-11       Impact factor: 5.191

7.  Sodium clavulanate potentiation of cephalosporin activity against clinical isolates of cephalothin-resistant Klebsiella pneumoniae.

Authors:  R T Jackson; L F Harris; R H Alford
Journal:  Antimicrob Agents Chemother       Date:  1978-07       Impact factor: 5.191
  7 in total
  6 in total

1.  Single-dose pharmacokinetics of intravenous clavulanic acid with amoxicillin in pediatric patients.

Authors:  U B Schaad; P A Casey; D L Cooper
Journal:  Antimicrob Agents Chemother       Date:  1983-02       Impact factor: 5.191

Review 2.  Amoxycillin/clavulanic acid: a review of its antibacterial activity, pharmacokinetics and therapeutic use.

Authors:  R N Brogden; A Carmine; R C Heel; P A Morley; T M Speight; G S Avery
Journal:  Drugs       Date:  1981-11       Impact factor: 9.546

3.  Pharmacokinetics of amoxicillin and clavulanic acid administered alone and in combination.

Authors:  D Adam; I de Visser; P Koeppe
Journal:  Antimicrob Agents Chemother       Date:  1982-09       Impact factor: 5.191

Review 4.  Penicillins. A current review of their clinical pharmacology and therapeutic use.

Authors:  Dilip Nathwani; Martin J Wood
Journal:  Drugs       Date:  1993-06       Impact factor: 9.546

5.  Antibacterial activity and kill kinetics of amoxicillin-clavulanic acid combinations against Escherichia coli and Klebsiella aerogenes.

Authors:  J E Fuglesang; T Bergan
Journal:  Infection       Date:  1983 Nov-Dec       Impact factor: 3.553

6.  Differential effect of impaired renal function on the kinetics of clavulanic acid and amoxicillin.

Authors:  F F Horber; F J Frey; C Descoeudres; A T Murray; F C Reubi
Journal:  Antimicrob Agents Chemother       Date:  1986-04       Impact factor: 5.191
  6 in total

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