Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Fluorimetric assays for cathepsin B and cathepsin H with methylcoumarylamide substrates.

Literature DB >> 6897924

Fluorimetric assays for cathepsin B and cathepsin H with methylcoumarylamide substrates.

Abstract

Benzyloxycarbonyl-phenylalanyl-arginine 4-methyl-7-coumarylamide was found to be an excellent substrate for the fluorimetric assay of cathepsin B, and arginine 4-methyl-7-coumarylamide for cathepsin H. Procedures were developed that are very convenient, and avoid the hazards associated with the use of naphthylamides.

Entities: Chemical Gene

Mesh：

Substances：

Year: 1980 PMID： 6897924 PMCID： PMC1162479 DOI： 10.1042/bj1870909

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

18 in total

1. On the substrate specificity of cathepsins B1 and B2 including a new fluorogenic substrate for cathepsin B1.

Authors: J K McDonald; S Ellis
Journal: Life Sci Date: 1975-10-15 Impact factor: 5.037

2. Statistical estimations in enzyme kinetics.

Authors: G N WILKINSON
Journal: Biochem J Date: 1961-08 Impact factor: 3.857

3. alpha-N-benzoylarginine-2-naphthylamide hydrolase (cathepsin B1 ?) from rat skin. II. Purification of the enzyme and demonstration of two inhibitors in the skin.

Authors: M Järvinen; V K Hopsu-Havu
Journal: Acta Chem Scand B Date: 1975

4. An improved color reagent for use in Barrett's assay of Cathepsin B.

Authors: A J Barrett
Journal: Anal Biochem Date: 1976-11 Impact factor: 3.365

5. Unsuitability of leucine naphthylamide for the histochemical demonstration of lysosomal proteolytic activity.

Authors: A J Barrett; A R Poole
Journal: Nature Date: 1969-10-18 Impact factor: 49.962

6. Leucine naphthylamide: an inappropriate [corrected] substrate for the histochemical detection of cathepsins B and B'.

Authors: J K McDonald; B B Zeitman; S Ellis
Journal: Nature Date: 1970-03-14 Impact factor: 49.962

7. A new assay for cathepsin B1 and other thiol proteinases.

Authors: A J Barrett
Journal: Anal Biochem Date: 1972-05 Impact factor: 3.365

8. On the size of the active site in proteases. I. Papain.

Authors: I Schechter; A Berger
Journal: Biochem Biophys Res Commun Date: 1967-04-20 Impact factor: 3.575

9. Cathepsin L. A new proteinase from rat-liver lysosomes.

Authors: H Kirschke; J Langner; B Wiederanders; S Ansorge; P Bohley
Journal: Eur J Biochem Date: 1977-04-01

10. Human cathepsin B1. Purification and some properties of the enzyme.

Authors: A J Barrett
Journal: Biochem J Date: 1973-04 Impact factor: 3.857

69 in total

Review 1. Using specificity to strategically target proteases.

Authors: Mark D Lim; Charles S Craik
Journal: Bioorg Med Chem Date: 2008-03-30 Impact factor: 3.641

2. Intestinal epithelial cells use two distinct pathways for HLA class II antigen processing.

Authors: R M Hershberg; P E Framson; D H Cho; L Y Lee; S Kovats; J Beitz; J S Blum; G T Nepom
Journal: J Clin Invest Date: 1997-07-01 Impact factor: 14.808

3. Purification and characterization of a metallo-endoproteinase from mouse kidney.

Authors: R J Beynon; J D Shannon; J S Bond
Journal: Biochem J Date: 1981-12-01 Impact factor: 3.857

4. L-trans-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) and its analogues as inhibitors of cysteine proteinases including cathepsins B, H and L.

Authors: A J Barrett; A A Kembhavi; M A Brown; H Kirschke; C G Knight; M Tamai; K Hanada
Journal: Biochem J Date: 1982-01-01 Impact factor: 3.857

10. Monitoring compartment-specific substrate cleavage by cathepsins B, K, L, and S at physiological pH and redox conditions.

Authors: Silvia Jordans; Sasa Jenko-Kokalj; Nicole M Kühl; Sofia Tedelind; Wolfgang Sendt; Dieter Brömme; Dusan Turk; Klaudia Brix
Journal: BMC Biochem Date: 2009-09-22 Impact factor: 4.059