Literature DB >> 6897541

The sequence of 3'-termini of mRNAs from early region III of adenovirus 2.

C M Ahmed, R Chanda, N Stow, B S Zain.   

Abstract

The cloned cDNA sequences corresponding to early region III transcripts (76.6-86.0 map units) of adenovirus 2 were analyzed with a view to determine the structure of their 3'-termini. The clones pE7, pE22 and pE34, which contain a part of or the entire coding sequence for the Mr 19000 glycoprotein, showed microheterogeneity with respect to the poly(A) addition site, with the polyadenylation occurring 17, 26, or 29 nucleotides downstream from the hexanucleotide, 5'-ATTAAA-3'. The clone pE17 which represents a copy of the mRNA ending at 86.0 map units showed the presence of the sequence 5'-AATAAA-3', 16 nucleotides before the poly(A) tail.

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Year:  1982        PMID: 6897541     DOI: 10.1016/0378-1119(82)90019-1

Source DB:  PubMed          Journal:  Gene        ISSN: 0378-1119            Impact factor:   3.688


  12 in total

1.  Identification of a novel sequence that governs both polyadenylation and alternative splicing in region E3 of adenovirus.

Authors:  H A Brady; W S Wold
Journal:  Nucleic Acids Res       Date:  1987-11-25       Impact factor: 16.971

2.  Virus deletion mutants that affect a 3' splice site in the E3 transcription unit of adenovirus 2.

Authors:  B M Bhat; H A Brady; W S Wold
Journal:  Mol Cell Biol       Date:  1985-09       Impact factor: 4.272

3.  mRNAs from human adenovirus 2 early region 4.

Authors:  A Virtanen; P Gilardi; A Näslund; J M LeMoullec; U Pettersson; M Perricaudet
Journal:  J Virol       Date:  1984-09       Impact factor: 5.103

4.  Selection of sequence elements that substitute for the standard AATAAA motif which signals 3' processing and polyadenylation of late simian virus 40 mRNAs.

Authors:  C Swimmer; T Shenk
Journal:  Nucleic Acids Res       Date:  1985-11-25       Impact factor: 16.971

Review 5.  Regulation of early adenovirus gene expression.

Authors:  J R Nevins
Journal:  Microbiol Rev       Date:  1987-12

6.  Human dihydropteridine reductase: characterisation of a cDNA clone and its use in analysis of patients with dihydropteridine reductase deficiency.

Authors:  H H Dahl; W Hutchison; W McAdam; S Wake; F J Morgan; R G Cotton
Journal:  Nucleic Acids Res       Date:  1987-03-11       Impact factor: 16.971

7.  ATTAAA as well as downstream sequences are required for RNA 3'-end formation in the E3 complex transcription unit of adenovirus.

Authors:  B M Bhat; W S Wold
Journal:  Mol Cell Biol       Date:  1985-11       Impact factor: 4.272

8.  Efficient coupled transcription and mRNA splicing in vitro using plasmids derived from early region 3 of adenovirus 2 and a nondefective adenovirus-simian virus 40 hybrid.

Authors:  S Pawar; C M Ahmed; R Watkins; S Zain
Journal:  Proc Natl Acad Sci U S A       Date:  1984-05       Impact factor: 11.205

9.  Novel deletion mutants that enhance a distant upstream 5' splice in the E3 transcription unit of adenovirus 2.

Authors:  S L Deutscher; B M Bhat; M H Pursley; C Cladaras; W S Wold
Journal:  Nucleic Acids Res       Date:  1985-08-26       Impact factor: 16.971

10.  Polyadenylic acid addition sites in the adenovirus type 2 major late transcription unit.

Authors:  J M Le Moullec; G Akusjärvi; P Stålhandske; U Pettersson; B Chambraud; P Gilardi; M Nasri; M Perricaudet
Journal:  J Virol       Date:  1983-10       Impact factor: 5.103

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