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Literature DB >> 6895484

Autoradiographic studies with 3H 1,25 (OH)2 vitamin D2 and 3H 25 (OH) vitamin D3 in rat parathyroid glands.

W E Stumpf, M Sar, F A Reid, S Huang, R Narbaitz, H F DeLuca.

Abstract

After injection of radiolabeled 1,35 (OH)s vitamin D3, nuclear concentration of radioactivity is observed in parenchymal cells o hte parathyroid gland in pregnant, adult male, and 10-day male neonatal rats. In competition studies with unlabeled 1,25 (OH)2 vitamin D3, but not with 25 (OH) vitamin D3, in contrast to 3H 1,25 (OH)2 vitamin D3, do not show nuclear concentration in cells of te parathyroid. The results of te autoradiographic studies suggest the presence of receptors for a direct effect of 1,35 (OH)2 vitamin D3 on the parathyroid gland for modulation of parathyroid hormone secretion.

Entities: Chemical Species

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Year: 1981 PMID： 6895484 DOI： 10.1007/bf00216737

Source DB: PubMed Journal: Cell Tissue Res ISSN： 0302-766X Impact factor: 5.249

15 in total

1. Response of chick parathyroid glands to the vitamin D metabolites, 1,25-dihydroxycholecalciferol and 24,25-dihydroxycholecalciferol.

Authors: H L Henry; A N Taylor; A W Norman
Journal: J Nutr Date: 1977-10 Impact factor: 4.798

Review 2. A survey of the hormonal factors that control calcium metabolism.

Authors: I MacIntyre; K W Colston; M Szelke; E Spanos
Journal: Ann N Y Acad Sci Date: 1978-04-28 Impact factor: 5.691

3. Probable sites for estrogen receptors in brain and pituitary.

Authors: W E Stumpf
Journal: J Neurovisc Relat Date: 1971

4. Control of 25-hydroxycholecalciferol metabolism by parathyroid glands.

Authors: M Garabedian; M F Holick; H F Deluca; I T Boyle
Journal: Proc Natl Acad Sci U S A Date: 1972-07 Impact factor: 11.205

5. Biological activity of 25-hydroxyergocalciferol in rats.

Authors: T Suda; H F DeLuca; Y Tanaka
Journal: J Nutr Date: 1970-09 Impact factor: 4.798

Review 6. Biosynthesis of parathyroid hormone.

Authors: J F Habener; B W Kemper; A Rich; J T Potts
Journal: Recent Prog Horm Res Date: 1976

Review 7. The role of autoradiographic and immunocytochemical techniques in the clarification of sites of metabolism and action of vitamin D.

Authors: R Narbaitz; W E Stumpf; M Sar
Journal: J Histochem Cytochem Date: 1981-01 Impact factor: 2.479

8. Target cells for 1,25-dihydroxyvitamin D3 in intestinal tract, stomach, kidney, skin, pituitary, and parathyroid.

Authors: W E Stumpf; M Sar; F A Reid; Y Tanaka; H F DeLuca
Journal: Science Date: 1979-12-07 Impact factor: 47.728

9. Decrease in serum immunoreactive parathyroid hormone in rats and in parathyroid hormone secretion in vitro by 1,25-dihydroxycholecalciferol.

Authors: B S Chertow; D J Baylink; J E Wergedal; M H Su; A W Norman
Journal: J Clin Invest Date: 1975-09 Impact factor: 14.808

Review 3. Vitamin D--soltriol the heliogenic steroid hormone: somatotrophic activator and modulator. Discoveries from histochemical studies lead to new concepts.

Authors: W E Stumpf
Journal: Histochemistry Date: 1988

4. The adrenal: a new target organ of the calciotropic hormone 1,25-dihydroxyvitamin D3.

Authors: S A Clark; W E Stumpf; C W Bishop; H F DeLuca; D H Park; T H Joh
Journal: Cell Tissue Res Date: 1986 Impact factor: 5.249

4 in total