Literature DB >> 6893469

Ivermectin, a new broad-spectrum antiparasitic agent.

J C Chabala, H Mrozik, R L Tolman, P Eskola, A Lusi, L H Peterson, M F Woods, M H Fisher, W C Campbell, J R Egerton, D A Ostlind.   

Abstract

22,23-Dihydroavermectin B1, ivermectin, derived from avermectin B1 by selective hydrogenation using Wilkinson's homogenous catalyst [Ph3P)3RhCl], was shown to be a highly effective drug for the treatment of a wide variety of metazoan parasitic diseases in animals.

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Year:  1980        PMID: 6893469     DOI: 10.1021/jm00184a014

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


  43 in total

1.  The inhibition of the sarcoplasmic/endoplasmic reticulum Ca2+-ATPase by macrocyclic lactones and cyclosporin A.

Authors:  Jonathan G Bilmen; Laura L Wootton; Francesco Michelangeli
Journal:  Biochem J       Date:  2002-08-15       Impact factor: 3.857

2.  Marine natural products as prototype agrochemical agents.

Authors:  Jiangnan Peng; Xiaoyu Shen; Khalid A El Sayed; D Charles Dunbar; Tony L Perry; Scott P Wilkins; Mark T Hamann; Steve Bobzin; Joseph Huesing; Robin Camp; Mike Prinsen; Dan Krupa; Margaret A Wideman
Journal:  J Agric Food Chem       Date:  2003-04-09       Impact factor: 5.279

3.  Avenolide, a Streptomyces hormone controlling antibiotic production in Streptomyces avermitilis.

Authors:  Shigeru Kitani; Kiyoko T Miyamoto; Satoshi Takamatsu; Elisa Herawati; Hiroyuki Iguchi; Kouhei Nishitomi; Miho Uchida; Tohru Nagamitsu; Satoshi Omura; Haruo Ikeda; Takuya Nihira
Journal:  Proc Natl Acad Sci U S A       Date:  2011-09-19       Impact factor: 11.205

4.  Bioconversion of avermectin into 27-OH avermectin.

Authors:  M Chartrain; R White; R Goegelman; K Gbewonyo; R Greasham
Journal:  J Ind Microbiol       Date:  1990-12

5.  Total synthesis of avermectin B1a revisited.

Authors:  Shuji Yamashita; Daisuke Hayashi; Aoi Nakano; Yujiro Hayashi; Masahiro Hirama
Journal:  J Antibiot (Tokyo)       Date:  2015-09-09       Impact factor: 2.649

Review 6.  Inhibitory glutamate receptor channels.

Authors:  T A Cleland
Journal:  Mol Neurobiol       Date:  1996-10       Impact factor: 5.590

7.  A review of the pharmacology and clinical uses of ivermectin.

Authors:  T B Barragry
Journal:  Can Vet J       Date:  1987-08       Impact factor: 1.008

8.  Antitumor effects of ivermectin at clinically feasible concentrations support its clinical development as a repositioned cancer drug.

Authors:  Mandy Juarez; Alejandro Schcolnik-Cabrera; Guadalupe Dominguez-Gomez; Alma Chavez-Blanco; Jose Diaz-Chavez; Alfonso Duenas-Gonzalez
Journal:  Cancer Chemother Pharmacol       Date:  2020-05-30       Impact factor: 3.333

Review 9.  A comprehensive review of glycosylated bacterial natural products.

Authors:  Sherif I Elshahawi; Khaled A Shaaban; Madan K Kharel; Jon S Thorson
Journal:  Chem Soc Rev       Date:  2015-11-07       Impact factor: 54.564

10.  Gates Grand Challenges Explorations award: Endectocides for Controlling Transmission of Mosquito-borne Diseases.

Authors:  Massamba Sylla; Kevin C Kobylinski; Brian D Foy
Journal:  Malariaworld J       Date:  2013-03
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