Literature DB >> 6893373

ts P1 and P3 genes are responsible for satisfactory level of attenuation of ts-1A2 recombinants bearing H1N1 or H3N2 surface antigens of influenza A virus.

J G Massicot, B R Murphy, K van Wyke, K Y Huang, R M Chanock.   

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Year:  1980        PMID： 6893373     DOI： 10.1016/0042-6822(80)90241-x

Source DB:  PubMed          Journal:  Virology        ISSN： 0042-6822            Impact factor:   3.616


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  6 in total

1.  Characterization of the temperature sensitive phenotype of the A/Ann Arbor/6/60 cold-adapted virus and its recombinants.

Authors:  B R Murphy; H F Maassab; F T Wood; R M Chanock
Journal:  Infect Immun       Date:  1981-05       Impact factor: 3.441

2.  Genetically engineered live attenuated influenza A virus vaccine candidates.

Authors:  N T Parkin; P Chiu; K Coelingh
Journal:  J Virol       Date:  1997-04       Impact factor: 5.103

3.  Evaluation of a phenotypic revertant of the A/Alaska/77-ts-1A2 reassortant virus in hamsters and in seronegative adult volunteers: further evidence that the temperature-sensitive phenotype is responsible for attenuation of ts-1A2 reassortant viruses.

Authors:  M D Tolpin; M L Clements; M M Levine; R E Black; A J Saah; W C Anthony; L Cisneros; R M Chanock; B R Murphy
Journal:  Infect Immun       Date:  1982-05       Impact factor: 3.441

4.  Production and level of genetic stability of an influenza A virus temperature-sensitive mutant containing two genes with ts mutations.

Authors:  B R Murphy; L J Markoff; N T Hosier; J G Massicot; R M Chanock
Journal:  Infect Immun       Date:  1982-07       Impact factor: 3.441

5.  Sequential addition of temperature-sensitive missense mutations into the PB2 gene of influenza A transfectant viruses can effect an increase in temperature sensitivity and attenuation and permits the rational design of a genetically engineered live influenza A virus vaccine.

Authors:  E K Subbarao; E J Park; C M Lawson; A Y Chen; B R Murphy
Journal:  J Virol       Date:  1995-10       Impact factor: 5.103

Review 6.  Why is temperature sensitivity important for the success of common respiratory viruses?

Authors:  Ronald Eccles
Journal:  Rev Med Virol       Date:  2020-08-10       Impact factor: 11.043
  6 in total

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