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Literature DB >> 6893264

[DNA-repair of lymphocytes during PUVA-treatment (author's transl)].

Abstract

In 20 psoriatic patients under PUVA maintenance treatment blood samples had been collected imediately before and after the UVA irradiation. The DNA-repair activity has been determined in the isolated lymphocytes by the incorporation of 3H-thymidine during the first 3 h (inhibition of the semiconservative replication by hydroxyurea). There is evidence for an increased repair activity in the lymphocytes after PUVA treatment whereas the lymphocytes exposed only to 8-MOP (before UVA irradiation) show lower values. The difference is statistically significant 45 and 90 min after irradiation, but not any more after 3 h.

Entities: Chemical Disease Species

Mesh：

Substances：
Furocoumarins

Year: 1980 PMID： 6893264 DOI： 10.1007/bf00569103

Source DB: PubMed Journal: Arch Dermatol Res ISSN： 0340-3696 Impact factor: 3.017

13 in total

1. Decreased circulating E rosette forming cells in psoralen UVA treated patients.

Authors: J P Ortonne; A L Claudy; A Alario; J Thivolet
Journal: Arch Dermatol Res Date: 1977-05-27 Impact factor: 3.017

2. Sister chromatid exchanges in photochemotherapy.

Authors: E C Wolff-Schreiner; D M Carter; H G Schwarzacher; K Wolff
Journal: J Invest Dermatol Date: 1977-10 Impact factor: 8.551

3. [Effects of UV-C and of 8-MOP + UV-A on the T- and B-population of human lymphocytes in vitro (author's transl)].

Authors: E Bohnert; G Bächtold; G Lischka; E G Jung
Journal: Arch Dermatol Res Date: 1977-10-27 Impact factor: 3.017

4. Decreased thymidine incorporation in circulating leukocytes after treatment of psoriasis with psoralen and long-wave ultraviolet light.

Authors: K H Kraemer; G D Weinstein
Journal: J Invest Dermatol Date: 1977-08 Impact factor: 8.551

5. [DNA-repair in lymphocytes after 8-MOP + UVA and UVC irradiation (author's transl)].

Authors: E Bohnert; B Badilatti; P Sidler; E G Jung
Journal: Arch Dermatol Res Date: 1979-05-04 Impact factor: 3.017

6. Psoralen/UVA treatment and chromosomes. II. Analyses of psoriasis patients.

Authors: A Brøgger; H Waksvik; P Thune
Journal: Arch Dermatol Res Date: 1978-05-31 Impact factor: 3.017

7. Sister chromatid exchanges in lymphocytes of psoriatics after treatment with 8-methoxypsoralen and long wave ultraviolet radiation.

Authors: D Mourelatos; M J Faed; P W Gould; B E Johnson; W Frain-Bell
Journal: Br J Dermatol Date: 1977-12 Impact factor: 9.302

[DNA-repair of lymphocytes during PUVA-treatment (author's transl)].

1. Decreased circulating E rosette forming cells in psoralen UVA treated patients.

2. Sister chromatid exchanges in photochemotherapy.

3. [Effects of UV-C and of 8-MOP + UV-A on the T- and B-population of human lymphocytes in vitro (author's transl)].

4. Decreased thymidine incorporation in circulating leukocytes after treatment of psoriasis with psoralen and long-wave ultraviolet light.

5. [DNA-repair in lymphocytes after 8-MOP + UVA and UVC irradiation (author's transl)].

6. Psoralen/UVA treatment and chromosomes. II. Analyses of psoriasis patients.

7. Sister chromatid exchanges in lymphocytes of psoriatics after treatment with 8-methoxypsoralen and long wave ultraviolet radiation.

8. UVA-induced inhibition of proliferation of PHA-stimulated lymphocytes from humans treated with 8-methoxypsoralen.

9. Dark effect of 8-methoxypsoralen (8-MOP) on lymphocytes.

10. Lymphocyte proliferation during PUVA therapy.

1. Xeroderma pigmentosum patients from Germany: clinical symptoms and DNA repair characteristics.