Literature DB >> 6893145

Trichloroethylene vapours do not produce dominant lethal mutations in male mice.

R Slacik-Erben, R Roll, G Franke, H Uehleke.   

Abstract

Exposure of male mice to trichloroethylene vapours during 24 h at levels or 50, 202 and 450 ppm did not reveal mutagenic effects in the dominant lethal assay. The following parameters were registered and evaluated: Fertilization rate, post-implantation loss, preemplantation loss and dominant lethal mutations.

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Year:  1980        PMID： 6893145     DOI： 10.1007/bf00303293

Source DB:  PubMed          Journal:  Arch Toxicol        ISSN： 0340-5761            Impact factor:   5.153


  18 in total

1.  Mutagenicity in vitro and potential carcinogenicity of chlorinated ethylenes as a function of metabolic oxiran formation.

Authors:  H Greim; G Bonse; Z Radwan; D Reichert; D Henschler
Journal:  Biochem Pharmacol       Date:  1975-11-01       Impact factor: 5.858

2.  Metabolic transformation of clinically used drugs to epoxides: new perspectives in drug-drug interactions.

Authors:  F Oesch
Journal:  Biochem Pharmacol       Date:  1976-09-01       Impact factor: 5.858

3.  Carcinogenicity of trichloroethylene: fact or artifact?

Authors:  D Henschler; E Eder; T Neudecker; M Metzler
Journal:  Arch Toxicol       Date:  1977-07-19       Impact factor: 5.153

4.  [Chromosome studies on trichloroethylene workers (author's transl)].

Authors:  H Konietzko; W Haberlandt; H Heilbronner; G Reill; H Weichardt
Journal:  Arch Toxicol       Date:  1978-06-16       Impact factor: 5.153

5.  Irreversible binding of 14C-labelled trichloroethylene to mice liver constituents in vivo and in vitro.

Authors:  H Uehleke; S Poplawski-Tabarelli
Journal:  Arch Toxicol       Date:  1977-08-09       Impact factor: 5.153

6.  Epoxides metabolically produced from some known carcinogens and from some clinically used drugs. I. Differences in mutagenicity.

Authors:  H R Glatt; F Oesch; A Frigerio; S Garattini
Journal:  Int J Cancer       Date:  1975-11-15       Impact factor: 7.396

7.  Covalent interaction of metabolites of the carcinogen trichloroethylene in rat hepatic microsomes.

Authors:  B L Van Duuren; S Banerjee
Journal:  Cancer Res       Date:  1976-07       Impact factor: 12.701

8.  Cytochrome P-450 mediated genetic activity and cytotoxicity of seven halogenated aliphatic hydrocarbons in Saccharomyces cerevisiae.

Authors:  D F Callen; C R Wolf; R M Philpot
Journal:  Mutat Res       Date:  1980-01       Impact factor: 2.433

9.  Carcinogenicity study of trichloroethylene by longterm inhalation in three animal species.

Authors:  D Henschler; W Romen; H M Elsässer; D Reichert; E Eder; Z Radwan
Journal:  Arch Toxicol       Date:  1980-02       Impact factor: 5.153

10.  Irreversible binding of 3-14C-antipyrine to hepatic protein in vivo and in metabolizing liver microsomes.

Authors:  S Tabarelli-Poplawski; H Uehleke
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1977-03       Impact factor: 3.000
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