| Literature DB >> 6883177 |
Abstract
Pig--mouse somatic cell hybrids were obtained by fusing pig lymphocytes with mouse cells of the RAG (HPTR-) line using polyethylene glycol. The expression of pig superoxide dismutase (SOD-1) activity in 11 hybrid clones as well as in the parental cells was investigated. Seven hybrid clones positive for the expression of pig SOD-1 displayed the corresponding parental RAG and pig bands of SOD-1 plus a heteropolymeric band of intermediate electrophoretic mobility. The positive and negative expression of pig SOD-1 was concordant with the retention and loss of pig chromosome No. 9, suggesting that the gene for pig SOD-1 is located on the chromosome No. 9 of the domestic pig.Entities:
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Year: 1983 PMID： 6883177 DOI： 10.1139/g83-037
Source DB: PubMed Journal: Can J Genet Cytol ISSN： 0008-4093