Literature DB >> 6882040

Assessment of nonsteroidal anti-inflammatory drug combinations by the polyurethane sponge implantation model in the rat.

R Garrett, B Manthey, B Vernon-Roberts, P M Brooks.   

Abstract

The anti-inflammatory effect of single doses and combinations of aspirin and commonly used nonsteroidal anti-inflammatory drugs was investigated by the polyurethane sponge implantation model of acute inflammation. Dose response curves were performed to delineate a suppressive (high) and nonsuppressive (low) dose of each drug prior to studying these doses in combination with aspirin. The results suggest that a combination of aspirin in either high or low dose does not increase the anti-inflammatory effect of other nonsteroidal anti-inflammatory drugs in this model of inflammation.

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Year:  1983        PMID： 6882040      PMCID： PMC1001259          DOI： 10.1136/ard.42.4.439

Source DB:  PubMed          Journal:  Ann Rheum Dis        ISSN： 0003-4967            Impact factor:   19.103


  11 in total

1.  Interactions of anti-rheumatic drugs.

Authors:  P M Brooks; M A Bell; D I Mason; W W Buchanan
Journal:  Agents Actions Suppl       Date:  1977

2.  The aspirin-ibuprofen interaction in rheumatoid arthritis.

Authors:  D M Grennan; D G Ferry; M E Ashworth; R E Kenny; M Mackinnon
Journal:  Br J Clin Pharmacol       Date:  1979-11       Impact factor: 4.335

3.  Interactions of aspirin with nonsteroidal antiinflammatory drugs in man.

Authors:  A Rubin; B E Rodda; P Warrick; C M Gruber; A S Ridolfo
Journal:  Arthritis Rheum       Date:  1973 Sep-Oct

4.  Interaction of aspirin with nonsteroidal anti-inflammatory drugs in rats.

Authors:  Z E Mielens; H P Drobeck; J Rozitis; V J Sansone
Journal:  J Pharm Pharmacol       Date:  1968-07       Impact factor: 3.765

5.  Naproxen-aspirin interactions in man.

Authors:  E J Segre; M Chaplin; E Forchielli; R Runkel; H Sevelius
Journal:  Clin Pharmacol Ther       Date:  1974-04       Impact factor: 6.875

6.  Interactions of aspirin, indomethacin and other drugs in adjuvant-induced arthritis in the rat.

Authors:  C G Van Arman; G W Nuss; E A Risley
Journal:  J Pharmacol Exp Ther       Date:  1973-11       Impact factor: 4.030

7.  Interactions of anti-inflammatory drugs in carrageenan-induced foot edema of the rat.

Authors:  K F Swingle; T J Grant; L W Jaques; D C Kvam
Journal:  J Pharmacol Exp Ther       Date:  1970-04       Impact factor: 4.030

8.  Assessment of anti-inflammatory drugs in the rat using subcutaneous implants of polyurethane foam impregnated with dead tubercle bacilli.

Authors:  A K Clarke; B Vernon-Roberts; H L Currey
Journal:  Ann Rheum Dis       Date:  1975-08       Impact factor: 19.103

9.  Ketoprofen-aspirin interactions.

Authors:  R L Williams; R A Upton; J N Buskin; R M Jones
Journal:  Clin Pharmacol Ther       Date:  1981-08       Impact factor: 6.875

10.  Flurbiprofen-aspirin interaction: a double-blind crossover study.

Authors:  P M Brooks; T K Khong
Journal:  Curr Med Res Opin       Date:  1977       Impact factor: 2.580
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  6 in total

1.  Professor Barrie Vernon-Roberts, AO, MD, BSc, PhD, FRCPath, FRCPA, FAOrthA (Hon), FRS.SA.

Authors:  K D Rainsford; D R Haynes
Journal:  Inflammopharmacology       Date:  2013-07-04       Impact factor: 4.473

2.  Evaluation of chemokine- and phlogistin-mediated leukocyte chemotaxis using an in vivo sponge model.

Authors:  J S Fine; J V Jackson; A Rojas-Triana; L A Bober
Journal:  Inflammation       Date:  2000-08       Impact factor: 4.092

3.  Salicylate-NSAID interactions.

Authors:  D M Grennan; L Aarons
Journal:  Ann Rheum Dis       Date:  1984-04       Impact factor: 19.103

4.  The effect of isoxicam-aspirin combinations on the polyurethane sponge implantation model in the rat.

Authors:  R Garrett; B Manthey; B Vernon-Roberts; P M Brooks
Journal:  Br J Clin Pharmacol       Date:  1986       Impact factor: 4.335

5.  Biodistribution of 64Cu in inflamed rats following administration of two anti-inflammatory copper complexes.

Authors:  S J Beveridge; I R Garrett; M W Whitehouse; B Vernon-Roberts; P M Brooks
Journal:  Agents Actions       Date:  1985-10

6.  Effect of Polymers on the Physicochemical Properties and Biological Performance of Fenoprofen Calcium Dihydrate-Triacetyl-β-Cyclodextrin Complex.

Authors:  Hussein O Ammar; Tarek S Makram; Shaimaa Mosallam
Journal:  Pharmaceutics       Date:  2017-07-03       Impact factor: 6.321
  6 in total

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