| Literature DB >> 6872915 |
Abstract
It was proved in this experiment that tetrandrine, one of the bisbenzylisoquinoline alkaloids, may inhibit the development of experimental silicosis on rats whether the drug was given to the animal right after dusting or after the formation of silicotic nodules. As compared to the silicotic control rats, lowering of total weight and collagen content of the lungs were shown and some degradation of collagen fibers was also indicated from the histopathological examination.Entities:
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Year: 1983 PMID： 6872915 DOI： 10.1016/0147-6513(83)90075-1
Source DB: PubMed Journal: Ecotoxicol Environ Saf ISSN： 0147-6513 Impact factor: 6.291