Literature DB >> 686864

Prostaglandin production in arthritis.

R A Sturge, D B Yates, D Gordon, M Franco, W Paul, A Bray, J Morley.   

Abstract

Inflammatory cell populations from synovial effusions or synovial villi in rheumatoid arthritis have been cultured in vitro. Prostaglandin productive capacity, measured by radioimmunoassay, showed the polymorphonuclear leucocyte rich populations from synovial effusions to be poor sources of PGE production whereas the synovial fragments produced substantial amounts of PGE activity. It is suggested that the macrophage is the major source of local prostaglandin formation both in gout and rheumatoid arthritis.

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Year:  1978        PMID： 686864      PMCID： PMC1000236          DOI： 10.1136/ard.37.4.315

Source DB:  PubMed          Journal:  Ann Rheum Dis        ISSN： 0003-4967            Impact factor:   19.103


  24 in total

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Authors:  M W ROPES; G A BENNETT; S COBB; R JACOX; R A JESSAR
Journal:  Bull Rheum Dis       Date:  1958-12

2.  Effects of anti-inflammatory drugs on macrophage prostaglandin biosynthesis [proceedings].

Authors:  M A Bray; D Gordon
Journal:  Br J Pharmacol       Date:  1976-07       Impact factor: 8.739

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Authors:  J B Smith; A L Willis
Journal:  Nat New Biol       Date:  1971-06-23

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Authors:  J R Vane
Journal:  Nat New Biol       Date:  1971-06-23

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Authors:  S H Ferreira; S Moncada; J R Vane
Journal:  Nat New Biol       Date:  1971-06-23

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Authors:  B Samuelsson; E Granström; K Green; M Hamberg; S Hammarström
Journal:  Annu Rev Biochem       Date:  1975       Impact factor: 23.643

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Authors:  R J Flower
Journal:  Pharmacol Rev       Date:  1974-03       Impact factor: 25.468

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Authors:  D Crook; A J Collins; P A Bacon; R Chan
Journal:  Ann Rheum Dis       Date:  1976-08       Impact factor: 19.103

9.  Transformation of arachidonic acid and homo-gamma-linolenic acid by rabbit polymorphonuclear leukocytes. Monohydroxy acids from novel lipoxygenases.

Authors:  P Borgeat; M Hamberg; B Samuelsson
Journal:  J Biol Chem       Date:  1976-12-25       Impact factor: 5.157

10.  Release of prostaglandin by mitogen- and antigen-stimulated leukocytes in culture.

Authors:  V A Ferraris; F R DeRubertis
Journal:  J Clin Invest       Date:  1974-08       Impact factor: 14.808
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  10 in total

Review 1.  Platelet activating factor and asthma.

Authors:  J Morley
Journal:  Agents Actions       Date:  1986-10

2.  Correlation of fatty acid composition of adipose tissue lipids and serum phosphatidylcholine and serum concentrations of micronutrients with disease duration in rheumatoid arthritis.

Authors:  L Jacobsson; F Lindgärde; R Manthorpe; B Akesson
Journal:  Ann Rheum Dis       Date:  1990-11       Impact factor: 19.103

3.  Plasma levels and urinary excretion of prostaglandins in patients with rheumatoid arthritis.

Authors:  O Laitinen; E Seppalä; M Nissilä; H Vapaatalo
Journal:  Clin Rheumatol       Date:  1983-12       Impact factor: 2.980

4.  Effect of in vivo administration of gold sodium thiomalate on rat macrophage function.

Authors:  R M Turkall; G A Warr; M F Tsan
Journal:  Agents Actions       Date:  1982-10

5.  Inhibition of prostaglandin biosynthesis by etodolac. I. Selective activities in arthritis.

Authors:  R G Neuman; B D Wilson; M Barkley; E S Kimball; B M Weichman; D D Wood
Journal:  Agents Actions       Date:  1987-06

6.  The influence of synovial fluid from patients with rheumatoid arthritis on the proliferation of peripheral blood lymphocytes and the prostanoid release from monocytes.

Authors:  M Seitz; W Deimann; D Gemsa
Journal:  Agents Actions       Date:  1981-12

7.  Enhanced prostanoid release from monocytes of patients with rheumatoid arthritis and active systemic lupus erythematosus.

Authors:  M Seitz; W Hunstein
Journal:  Ann Rheum Dis       Date:  1985-07       Impact factor: 19.103

8.  Change of prostaglandin E level in joint fluids after treatment with flurbiprofen in patients with rheumatoid arthritis and osteoarthritis.

Authors:  M Tokunaga; K Ohuchi; S Yoshizawa; S Tsurufuji; A Rikimaru; E Wakamatsu
Journal:  Ann Rheum Dis       Date:  1981-10       Impact factor: 19.103

9.  Synthesis of arachidonate cyclo-oxygenase products by rheumatoid and nonrheumatoid synovial lining in nonproliferative organ culture.

Authors:  J A Salmon; G A Higgs; J R Vane; L Bitensky; J Chayen; B Henderson; B Cashman
Journal:  Ann Rheum Dis       Date:  1983-02       Impact factor: 19.103

10.  The synovial prostaglandin system in chronic inflammatory arthritis: differential effects of steroidal and nonsteroidal anti-inflammatory drugs.

Authors:  S Bombardieri; P Cattani; G Ciabattoni; O Di Munno; G Pasero; C Patrono; E Pinca; F Pugliese
Journal:  Br J Pharmacol       Date:  1981-08       Impact factor: 8.739
  10 in total

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