Literature DB >> 6867180

Propranolol-epinephrine interaction: a potential disaster.

C A Foster, S J Aston.   

Abstract

Presented here are six examples of potentially life-threatening propranolol-epinephrine interactions. The only report found that warns of a deleterious clinical interaction between propranolol and epinephrine appeared in 1980. With widespread use of propranolol for approved and unapproved conditions, the population at risk is significant. All physicians and dentists using local anesthetic with epinephrine should be aware of this interaction.

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Year:  1983        PMID: 6867180     DOI: 10.1097/00006534-198307000-00017

Source DB:  PubMed          Journal:  Plast Reconstr Surg        ISSN: 0032-1052            Impact factor:   4.730


  12 in total

1.  Essentials of local anesthetic pharmacology.

Authors:  Daniel E Becker; Kenneth L Reed
Journal:  Anesth Prog       Date:  2006

Review 2.  beta-blockers. Drug interactions of clinical significance.

Authors:  I Blaufarb; T M Pfeifer; W H Frishman
Journal:  Drug Saf       Date:  1995-12       Impact factor: 5.606

Review 3.  Adverse drug interactions.

Authors:  Daniel E Becker
Journal:  Anesth Prog       Date:  2011

4.  Basic and clinical pharmacology of autonomic drugs.

Authors:  Daniel E Becker
Journal:  Anesth Prog       Date:  2012

Review 5.  Local anesthetics: review of pharmacological considerations.

Authors:  Daniel E Becker; Kenneth L Reed
Journal:  Anesth Prog       Date:  2012

Review 6.  Adverse effects and drug interactions associated with local and regional anaesthesia.

Authors:  M Naguib; M M Magboul; A H Samarkandi; M Attia
Journal:  Drug Saf       Date:  1998-04       Impact factor: 5.606

7.  Epinephrine-containing test dose during beta-blockade.

Authors:  K Mackie; A Lam
Journal:  J Clin Monit       Date:  1991-07

Review 8.  Drug management in skin surgery.

Authors:  C Lawrence
Journal:  Drugs       Date:  1996-12       Impact factor: 9.546

9.  Cardiovascular alterations after injection of 2% lidocaine with norepinephrine 1:50,000 (xylestesin) in rats.

Authors:  Fatima Neves Faraco; Paschoal Laercio Armonia; Stanley F Malamed
Journal:  Anesth Prog       Date:  2007

10.  Local anesthesia in reduction mastoplasty for out-patient surgery.

Authors:  A A Mottura
Journal:  Aesthetic Plast Surg       Date:  1992       Impact factor: 2.326

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