Literature DB >> 6865763

The BB Wistar rat: an experimental model for the study of diabetic retinopathy.

A A Sima, R Garcia-Salinas, P K Basu.   

Abstract

Diabetic retinopathy was studied in the spontaneously diabetic BB Wistar rat with respect to qualitative and quantitative structural changes. Trypsin-digested retinal preparations revealed after 8 to 11 months of diabetes a decrease in the pericyte/endothelial cell ratio. Quantitative ultrastructural examinations showed no increase in the vascularity or in basement-membrane thickness in diabetic animals. However, retinal capillaries showed not infrequently occlusions by fibrin and platelet thrombi.

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Mesh：

Year:  1983        PMID： 6865763     DOI： 10.1016/s0026-0495(83)80027-4

Source DB:  PubMed          Journal:  Metabolism        ISSN： 0026-0495            Impact factor:   8.694


  9 in total

1.  Response of rat retinal capillary pericytes and endothelial cells to glucose.

Authors:  Jun Makita; Ken-ichi Hosoya; Peng Zhang; Peter F Kador
Journal:  J Ocul Pharmacol Ther       Date:  2010-11-20       Impact factor: 2.671

2.  Cultured retinal capillary pericytes die by apoptosis after an abrupt fluctuation from high to low glucose levels: a comparative study with retinal capillary endothelial cells.

Authors:  W Li; X Liu; M Yanoff; S Cohen; X Ye
Journal:  Diabetologia       Date:  1996-05       Impact factor: 10.122

3.  HbA1 in assessment of metabolic control in diabetic BB/E rats.

Authors:  F J Tames; J D Baird; A J Bone
Journal:  Diabetologia       Date:  1990-05       Impact factor: 10.122

4.  Liver perisinusoidal fibrosis in BB rats with or without overt diabetes.

Authors:  D Bernuau; R Guillot; A M Durand-Schneider; P Poussier; A Moreau; G Feldmann
Journal:  Am J Pathol       Date:  1985-07       Impact factor: 4.307

5.  MPV may reflect subcinical platelet activation in diabetic patients with and without diabetic retinopathy.

Authors:  M Citirik; E Beyazyildiz; M Simsek; O Beyazyildiz; I C Haznedaroglu
Journal:  Eye (Lond)       Date:  2014-12-19       Impact factor: 3.775

Review 6.  Diabetic Retinopathy: From Animal Models to Cellular Signaling.

Authors:  Priyamvada M Pitale; Marina S Gorbatyuk
Journal:  Int J Mol Sci       Date:  2022-01-27       Impact factor: 6.208

7.  High energy diets-induced metabolic and prediabetic painful polyneuropathy in rats.

Authors:  Fang Xie; Han Fu; Jun-Feng Hou; Kai Jiao; Michael Costigan; Jun Chen
Journal:  PLoS One       Date:  2013-02-25       Impact factor: 3.240

Review 8.  Animal models of diabetic retinopathy: summary and comparison.

Authors:  Angela Ka Wai Lai; Amy C Y Lo
Journal:  J Diabetes Res       Date:  2013-10-27       Impact factor: 4.011

9.  Relationship between Altered Platelet Morphological Parameters and Retinopathy in Patients with Type 2 Diabetes Mellitus.

Authors:  Tolga Yilmaz; Ahu Yilmaz
Journal:  J Ophthalmol       Date:  2016-04-12       Impact factor: 1.909
  9 in total

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