Literature DB >> 686252

Oxolinic acid for the treatment of chronic gastrointestinal Shigella carriers.

B S Ribner, E H Freimer.   

Abstract

Two patients were long-term gastrointestinal carriers of Shigella flexneri for 23 mo and 6 mo, respectively. Neither patient responded to oral antibiotics, despite in vitro sensitivity of the bacteria to the antibiotics administered. Oral oxolinic acid produced immediate cessation of the carrier state in both patients, with resolution of minor but persistent physical complaints.

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Year:  1978        PMID： 686252     DOI： 10.4269/ajtmh.1978.27.840

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN： 0002-9637            Impact factor:   2.345


  2 in total

1.  Two studies evaluating the safety and immunogenicity of a live, attenuated Shigella flexneri 2a vaccine (SC602) and excretion of vaccine organisms in North American volunteers.

Authors:  David E Katz; Trinka S Coster; Marcia K Wolf; Fernando C Trespalacios; Dani Cohen; Guy Robins; Antoinette B Hartman; Malabi M Venkatesan; David N Taylor; Thomas L Hale
Journal:  Infect Immun       Date:  2004-02       Impact factor: 3.441

2.  In vitro antibacterial activity of norfloxacin (MK-0366, AM-715) and other agents against gastrointestinal tract pathogens.

Authors:  D L Shungu; E Weinberg; H H Gadebusch
Journal:  Antimicrob Agents Chemother       Date:  1983-01       Impact factor: 5.191
  2 in total

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