Literature DB >> 6862445

The distribution and interaction of haemoglobin variants and the beta thalassaemia gene in Liberia.

U Bienzle, H Komp, M Feldheim, A Reimer, E Steffen, I Guggenmoos-Holzmann.   

Abstract

In a population survey in Liberia, West Africa, 12 major tribes were examined for the prevalence of Hb S, Hb C, and the beta thalassaemia (beta Thal) gene. Hb C is rare; Hb S and beta Thal occur in polymorphic frequencies. The distribution of both genes shows an inverse correlation. The beta Thal trait was diagnosed by quantitation of Hb A2 on DE 52-microchromatography. This method proved to be reliable and useful for mass screening.

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Year:  1983        PMID： 6862445     DOI： 10.1007/bf00274769

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  15 in total

1.  Thalassaemia in northern Liberia. A survey in the Mount Nimba area.

Authors:  M C Willcox
Journal:  J Med Genet       Date:  1975-03       Impact factor: 6.318

2.  Estimation of small percentages of foetal haemoglobin.

Authors:  K BETKE; H R MARTI; I SCHLICHT
Journal:  Nature       Date:  1959-12-12       Impact factor: 49.962

3.  [Demonstration of fetal hemoglobin in erythrocytes of a blood smear].

Authors:  E KLEIHAUER; H BRAUN; K BETKE
Journal:  Klin Wochenschr       Date:  1957-06-15

4.  The distribution of the sickle cell gene in Liberia.

Authors:  F B LIVINGSTONE
Journal:  Am J Hum Genet       Date:  1958-03       Impact factor: 11.025

5.  Date on the occurrence of hemoglobin C and other abnormal hemoglobins in some African populations.

Authors:  J HIERNAUZ; J LINHARD; F B LIVINGSTONE; J V NEEL; A ROBINSON; W W ZUELZER
Journal:  Am J Hum Genet       Date:  1956-09       Impact factor: 11.025

6.  Hemoglobin A 2 and malaria.

Authors:  G J Esan; U Bienzle; G Hiller; T A Adesina
Journal:  Am J Trop Med Hyg       Date:  1973-03       Impact factor: 2.345

7.  Hemoglobin history in West Africa.

Authors:  F B Livingstone
Journal:  Hum Biol       Date:  1976-09       Impact factor: 0.553

8.  Thalassaemia major with complete suppression of HbA production in a Ghanaian girl.

Authors:  B Ringelhann; A L Rudwick
Journal:  Acta Haematol       Date:  1972       Impact factor: 2.195

9.  Haemoglobin variants, beta-thalassaemia and G-6-PD types in Liberia.

Authors:  M C Willcox; L Beckman
Journal:  Hum Hered       Date:  1981       Impact factor: 0.444

10.  Malaria and haemoglobin A2 levels in northern Liberia.

Authors:  M Willcox; J Brohult; V Sirleaf; E Bengtsson
Journal:  Trans R Soc Trop Med Hyg       Date:  1979       Impact factor: 2.184
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  2 in total

1.  Sickle cell-beta +-thalassaemia: a haematological and clinical study in Liberia.

Authors:  U Bienzle; R Kappes; A Reimer; M Feldheim; F W Tischendorf; E Kohne
Journal:  Blut       Date:  1983-11

2.  Novel hemostatic biomolecules based on elastin-like polypeptides and the self-assembling peptide RADA-16.

Authors:  Shasha Yang; Sili Wei; Yun Mao; Hanxue Zheng; Juantao Feng; Jihong Cui; Xin Xie; Fulin Chen; Honmgmin Li
Journal:  BMC Biotechnol       Date:  2018-03-07       Impact factor: 2.563
  2 in total

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