Literature DB >> 6862436

Tandem translocation t(14;14) in isolated and clonal cells in ataxia telangiectasia are different.

A Aurias, B Dutrillaux, C Griscelli.   

Abstract

In a patient affected by ataxia telangiectasia (AT), an invading clone with a t(14;14) was found in PHA-, but not in pokeweed-stimulated, lymphocytes. With high resolution R-banding, the proximal breakage was visualized at the junction of bands q11.1-q11.2. This breakpoint differs from that (q12) of noninvading rearrangements of chromosome 14 in AT and non-AT patients. These differences are discussed.

Entities:  

Mesh：

Substances：

Year:  1983        PMID： 6862436     DOI： 10.1007/bf00274754

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  8 in total

1.  Specific chromosome aberrations in ataxia telangiectasia.

Authors:  J M Oxford; D G Harnden; J M Parrington; J D Delhanty
Journal:  J Med Genet       Date:  1975-09       Impact factor: 6.318

2.  [Cytogenetic analysis of 21 cases of ataxia telangiectasia].

Authors:  A Aurias
Journal:  J Genet Hum       Date:  1981-09

3.  [Correlation between variant translocation and the expression of immunoglobulin light chains in Burkitt-type lymphomas and leukemias].

Authors:  G Lenoir; J L Preud'homme; A Bernheim; R Berger
Journal:  C R Seances Acad Sci III       Date:  1981-11-02

4.  Human immunoglobulin heavy chain genes map to a region of translocations in malignant B lymphocytes.

Authors:  I R Kirsch; C C Morton; K Nakahara; P Leder
Journal:  Science       Date:  1982-04-16       Impact factor: 47.728

5.  High frequencies of inversions and translocations of chromosomes 7 and 14 in ataxia telangiectasia.

Authors:  A Aurias; B Dutrillaux; D Buriot; J Lejeune
Journal:  Mutat Res       Date:  1980-02       Impact factor: 2.433

6.  Tandem duplication q14 and dicentric formation by end-to-end chromosome fusions in ataxia telandiectasia (AT). Clinical and cytogenetic findings in 5 patients.

Authors:  K Hayashi; W Schmid
Journal:  Humangenetik       Date:  1975-11-06

7.  Rearrangement of genetic information may produce immunoglobulin diversity.

Authors:  M Weigert; L Gatmaitan; E Loh; J Schilling; L Hood
Journal:  Nature       Date:  1978 Dec 21-28       Impact factor: 49.962

8.  [Non random position of metaphasic chromosomes. IV. Study of translocations t(7;14)(p14;q12) and t(7;14)(q35;q12)].

Authors:  A Aurias; B Dutrillaux; J L Antoine; M Prieur
Journal:  Ann Genet       Date:  1982
  8 in total
  10 in total

1.  New data on clonal anomalies of chromosome 14 in ataxia telangiectasia: tct(14;14) and inv(14).

Authors:  A Aurias; M F Croquette; J P Nuyts; C Griscelli; B Dutrillaux
Journal:  Hum Genet       Date:  1986-01       Impact factor: 4.132

2.  Juxtaposition of the T-cell receptor alpha-chain locus (14q11) and a region (14q32) of potential importance in leukemogenesis by a 14;14 translocation in a patient with T-cell chronic lymphocytic leukemia and ataxia-telangiectasia.

Authors:  M P Davey; V Bertness; K Nakahara; J P Johnson; O W McBride; T A Waldmann; I R Kirsch
Journal:  Proc Natl Acad Sci U S A       Date:  1988-12       Impact factor: 11.205

3.  The breakpoint of an inversion of chromosome 14 in a T-cell leukemia: sequences downstream of the immunoglobulin heavy chain locus are implicated in tumorigenesis.

Authors:  R Baer; A Heppell; A M Taylor; P H Rabbitts; B Boullier; T H Rabbitts
Journal:  Proc Natl Acad Sci U S A       Date:  1987-12       Impact factor: 11.205

4.  An artifact in evaluation of paternal age trends for Down syndrome.

Authors:  E B Hook; P K Cross
Journal:  Hum Genet       Date:  1984       Impact factor: 4.132

5.  Inversion (14)(q12qter) or (q11.2q32.3): the most frequently acquired rearrangement in lymphocytes.

Authors:  A Aurias; J Couturier; A M Dutrillaux; B Dutrillaux; F Herpin; E Lamoliatte; M Lombard; M Muleris; M Paravatou; M Prieur
Journal:  Hum Genet       Date:  1985       Impact factor: 4.132

Review 6.  Ataxia-telangiectasia: an inherited disorder of ionizing-radiation sensitivity in man. Progress in the elucidation of the underlying biochemical defect.

Authors:  P J McKinnon
Journal:  Hum Genet       Date:  1987-03       Impact factor: 4.132

7.  Growth of large chromosomally abnormal T cell clones in ataxia telangiectasia patients is associated with translocation at 14q11. A model for other T cell neoplasia.

Authors:  R J Hollis; A A Kennaugh; S V Butterworth; A M Taylor
Journal:  Hum Genet       Date:  1987-08       Impact factor: 4.132

8.  A subpopulation of t(2;14)(p11;q32) cells in ataxia telangiectasia B lymphocytes.

Authors:  S V Butterworth; A M Taylor
Journal:  Hum Genet       Date:  1986-08       Impact factor: 4.132

9.  The chromosome breakpoint at 14q32 in an ataxia telangiectasia t(14;14) T cell clone is different from the 14q32 breakpoint in Burkitts and an inv(14) T cell lymphoma.

Authors:  A A Kennaugh; S V Butterworth; R Hollis; R Baer; T H Rabbitts; A M Taylor
Journal:  Hum Genet       Date:  1986-07       Impact factor: 4.132

10.  Cytogenetic investigations in a family with ataxia telangiectasia.

Authors:  M W Humphreys; N C Nevin; M A Wooldridge
Journal:  Hum Genet       Date:  1989-08       Impact factor: 4.132
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.