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Literature DB >> 6854311

The activity of monoamine oxidase -A and -B in brains from chronic alcoholics.

L Oreland, A Wiberg, B Winblad, C J Fowler, C G Gottfries, K Kiianmaa.

Abstract

The activity of monoamine oxidase--A was found to be lower in homogenates of hypothalamus and caudate nucleus, but not in cortex of the gyrus cinguli and hippocampus, from chronic alcoholics with respect to homogenates from autopsy cases without histories of alcohol abuse. The activity of monoamine oxidase--B was also lower in the alcoholics, but this could be due to the selective effect of age upon this enzyme form, since the alcoholics were younger than controls. No difference was found for either monoamine oxidase -A or -B activities in brain homogenates from an alcohol preferring (AA) strain of rats, with respect to those from a water preferring (ANA) strain.

Entities: Chemical Disease Gene Species

Mesh：

Substances：
Monoamine Oxidase

Year: 1983 PMID： 6854311 DOI： 10.1007/bf01243375

Source DB: PubMed Journal: J Neural Transm Impact factor: 3.575

32 in total

1. Some kinetic and inhibition properties of human brain mitochondrial monoamine oxidase (EC 1.4.3.4).

Authors: M Jain; E Bakutis; T Gayle; P Lansky
Journal: Neurobiology Date: 1974

2. Deamination of 5-hydroxytryptamine by both forms of monoamine oxidase in the rat brain.

Authors: C J Fowler; K F Tipton
Journal: J Neurochem Date: 1982-03 Impact factor: 5.372

3. Alcoholism and cerebral atrophy: a study of 50 patients with CT scan and psychologic testing.

Authors: J Lusins; S Zimberg; H Smokler; K Gurley
Journal: Alcohol Clin Exp Res Date: 1980-10 Impact factor: 3.455

4. Studies on monoamine oxidase. (Report XXV). Effects of alcohols on beef liver mitochondrial monoamine oxidase.

Authors: Y Kurosawa
Journal: Jpn J Pharmacol Date: 1974-10

5. Platelet monoamine oxidase activity in mental disorders: 2. Affective psychoses and suicidal behavior.

Authors: C G Gottfries; L von Knorring; L Oreland
Journal: Prog Neuropsychopharmacol Date: 1980

6. Multiple binding sites of human brain and liver monoamine oxidase: substrate specificities, selective inhibitions, and attempts to separate enzyme forms.

Authors: H L White; A T Glassman
Journal: J Neurochem Date: 1977-12 Impact factor: 5.372

7. The biochemical high-risk paradigm: behavioral and familial correlates of low platelet monoamine oxidase activity.

Authors: M S Buchsbaum; R D Coursey; D L Murphy
Journal: Science Date: 1976-10-15 Impact factor: 47.728

8. Substrate- and stereoselective inhibitor of human brain monoamine oxidase by 4-dimethylamino-alpha, 2-dimethylphenethylamine (FLA 336).

Authors: C J Fowler; L Oreland
Journal: J Pharm Pharmacol Date: 1981-06 Impact factor: 3.765

5. Effect of voluntary alcohol consumption on Maoa expression in the mesocorticolimbic brain of adult male rats previously exposed to prolonged maternal separation.

Authors: M Bendre; E Comasco; I Nylander; K W Nilsson
Journal: Transl Psychiatry Date: 2015-12-08 Impact factor: 6.222

5 in total

The activity of monoamine oxidase -A and -B in brains from chronic alcoholics.

1. Some kinetic and inhibition properties of human brain mitochondrial monoamine oxidase (EC 1.4.3.4).

2. Deamination of 5-hydroxytryptamine by both forms of monoamine oxidase in the rat brain.

3. Alcoholism and cerebral atrophy: a study of 50 patients with CT scan and psychologic testing.

4. Studies on monoamine oxidase. (Report XXV). Effects of alcohols on beef liver mitochondrial monoamine oxidase.

5. Platelet monoamine oxidase activity in mental disorders: 2. Affective psychoses and suicidal behavior.

6. Multiple binding sites of human brain and liver monoamine oxidase: substrate specificities, selective inhibitions, and attempts to separate enzyme forms.

7. The biochemical high-risk paradigm: behavioral and familial correlates of low platelet monoamine oxidase activity.

8. Substrate- and stereoselective inhibitor of human brain monoamine oxidase by 4-dimethylamino-alpha, 2-dimethylphenethylamine (FLA 336).

9. The effect of age on the activity and molecular properties of human brain monoamine oxidase.

10. Brain monoamine oxidase activity after chronic ethanol treatment of rats.

Review 1. The AA and ANA rat lines, selected for differences in voluntary alcohol consumption.

2. Brain gamma-aminobutyrate transaminase and monoamine oxidase activities in suicide victims.

3. Greater monoamine oxidase a binding in alcohol dependence.

Review 4. Dopamine-derived alkaloids in alcoholism and in Parkinson's and Huntington's diseases.

5. Effect of voluntary alcohol consumption on Maoa expression in the mesocorticolimbic brain of adult male rats previously exposed to prolonged maternal separation.