Literature DB >> 6852829

Coincidence between fragile site expression and interstitial deletion of chromosome 11 in a case of myelofibrosis.

M Sessarego, F Ajmar, R Ravazzolo, G L Bianchi Scarrà, C Garrè, P Boccaccio.   

Abstract

Cytogenetic examination of multiple peripheral blood cultures of a patient with myelofibrosis with myeloid metaplasia revealed the presence of an interstitial deletion of the long arm of chromosome 11, del(11)(q13q21). A folic acid dependent fragile site fra(11)(q13) was found in about 12% of the cells. The possible correlation between constitutional fragile site and acquired chromosomal alteration is discussed briefly.

Entities:  

Mesh：

Year:  1983        PMID： 6852829     DOI： 10.1007/bf00284671

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  5 in total

1.  High resolution of human chromosomes.

Authors:  J J Yunis
Journal:  Science       Date:  1976-03-26       Impact factor: 47.728

2.  Heritable fragile sites on human chromosomes I. Factors affecting expression in lymphocyte culture.

Authors:  G R Sutherland
Journal:  Am J Hum Genet       Date:  1979-03       Impact factor: 11.025

3.  Heritable fragile sites on human chromosomes II. Distribution, phenotypic effects, and cytogenetics.

Authors:  G R Sutherland
Journal:  Am J Hum Genet       Date:  1979-03       Impact factor: 11.025

4.  Cytogenetic abnormalities in a patient with hypercalcemia and papillary thyroid carcinoma.

Authors:  S Pathak; T C Hsu; N Samaan; R C Hickey
Journal:  Hum Genet       Date:  1982       Impact factor: 4.132

5.  Acute monocytic leukemia chromosome studies.

Authors:  R Berger; A Bernheim; F Sigaux; M T Daniel; F Valensi; G Flandrin
Journal:  Leuk Res       Date:  1982       Impact factor: 3.156
  5 in total
  5 in total

1.  Fragile sites and structural rearrangements in cancer.

Authors:  M De Braekeleer; B Smith; C C Lin
Journal:  Hum Genet       Date:  1985       Impact factor: 4.132

2.  Further localization of ETS1 indicates that the chromosomal rearrangement in Ewing sarcoma does not occur at fra(11)(q23).

Authors:  R N Simmers; G R Sutherland
Journal:  Hum Genet       Date:  1988-02       Impact factor: 4.132

3.  Folic acid sensitive fragile sites are not limited to the human karyotype. Demonstration of nonrandom gaps and breaks in the Persian vole Ellobius lutescens Th. inducible by methotrexate, fluorodeoxyuridine, and aphidicolin.

Authors:  M Djalali; G Barbi; P Steinbach
Journal:  Hum Genet       Date:  1985       Impact factor: 4.132

4.  Expression of fragile sites in childhood acute lymphoblastic leukemia patients and normal controls.

Authors:  P N Rao; N A Heerema; C G Palmer
Journal:  Hum Genet       Date:  1988-08       Impact factor: 4.132

5.  Defective erythropoiesis in primary myelofibrosis associated with a chromosome 11 abnormality.

Authors:  W N Patton; C M Bunce; S Larkins; G Brown
Journal:  Br J Cancer       Date:  1991-07       Impact factor: 7.640
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.