Literature DB >> 6851305

Primary treatment of breast cancer in elderly women with Tamoxifen.

J W Bradbeer, J Kyngdon.   

Abstract

One hundred and sixty-one female patients, over the age of 70, with breast cancer were treated by Tamoxifen alone in a pilot phase II study. 61% showed objective regression of the disease and in 27% there was complete remission. The treatment was well tolerated and the survival rate compared favourably to that following conventional methods of treatment. An accurate assessment of the method awaits a randomized clinical trial.

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Year:  1983        PMID: 6851305

Source DB:  PubMed          Journal:  Clin Oncol        ISSN: 0305-7399


  21 in total

1.  Treatment of elderly patients with breast cancer.

Authors:  J M Dixon
Journal:  BMJ       Date:  1992-04-18

2.  Poor response of breast cancer to tamoxifen.

Authors:  P J McDonald; R Carpenter; G T Royle; I Taylor
Journal:  Postgrad Med J       Date:  1990-12       Impact factor: 2.401

3.  Is surgical management compromised in elderly patients with breast cancer?

Authors:  H J Wanebo; B Cole; M Chung; M Vezeridis; B Schepps; J Fulton; K Bland
Journal:  Ann Surg       Date:  1997-05       Impact factor: 12.969

Review 4.  Tamoxifen and mastalgia. An emerging indication.

Authors:  I S Fentiman
Journal:  Drugs       Date:  1986-12       Impact factor: 9.546

Review 5.  Breast cancer in the elderly.

Authors:  M Bellet; C Alonso; B Ojeda
Journal:  Postgrad Med J       Date:  1995-11       Impact factor: 2.401

6.  Tamoxifen as primary treatment of breast cancer in elderly or frail patients: a practical management.

Authors:  S G Allan; A Rodger; J F Smyth; R C Leonard; U Chetty; A P Forrest
Journal:  Br Med J (Clin Res Ed)       Date:  1985-02-02

Review 7.  Tamoxifen. A reappraisal of its pharmacodynamic and pharmacokinetic properties, and therapeutic use.

Authors:  M M Buckley; K L Goa
Journal:  Drugs       Date:  1989-04       Impact factor: 9.546

8.  Breast cancer in the elderly.

Authors:  S E Singletary; R Shallenberger; V F Guinee
Journal:  Ann Surg       Date:  1993-11       Impact factor: 12.969

9.  Comparison of mastectomy with tamoxifen for treating elderly patients with operable breast cancer.

Authors:  J F Robertson; J H Todd; I O Ellis; C W Elston; R W Blamey
Journal:  BMJ       Date:  1988 Aug 20-27

10.  ERICA predicts response to tamoxifen in elderly women with breast cancer.

Authors:  N Davies; G Moir; R Carpenter; A Cuthbert; A Herbert; G T Royle; I Taylor
Journal:  Ann R Coll Surg Engl       Date:  1991-11       Impact factor: 1.891

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