Literature DB >> 1759765

ERICA predicts response to tamoxifen in elderly women with breast cancer.

N Davies1, G Moir, R Carpenter, A Cuthbert, A Herbert, G T Royle, I Taylor.   

Abstract

Oestrogen receptor status has been determined by an immunocytochemical assay using fine-needle aspiration samples of primary breast cancers in elderly patients. In a prospective study 56 patients were treated with tamoxifen only. Satisfactory assays were achieved in 49 patients. Disease was controlled by tamoxifen in 32 of 35 (91%) patients with oestrogen receptor positive tumours, compared with only 1 (7%) of 14 who were receptor negative. Immunocytochemical assay on fine-needle aspiration samples is relatively non-invasive and simple to perform, it accurately predicts response to tamoxifen in elderly patients and can be used to select patients for tamoxifen only therapy.

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Year:  1991        PMID： 1759765      PMCID： PMC2499444     

Source DB:  PubMed          Journal:  Ann R Coll Surg Engl        ISSN： 0035-8843            Impact factor:   1.891


  15 in total

1.  Relation between immunocytochemical estimation of oestrogen receptor in elderly patients with primary breast cancer and response to tamoxifen.

Authors:  D J Gaskell; R A Hawkins; K Sangsterl; U Chetty; A P Forrest
Journal:  Lancet       Date:  1989-05-13       Impact factor: 79.321

2.  Prospective randomised trial of tamoxifen versus surgery in elderly patients with breast cancer.

Authors:  J C Gazet; C Markopoulos; H T Ford; R C Coombes; J M Bland; R C Dixon
Journal:  Lancet       Date:  1988-03-26       Impact factor: 79.321

3.  Tamoxifen as primary treatment of breast cancer in elderly or frail patients: a practical management.

Authors:  S G Allan; A Rodger; J F Smyth; R C Leonard; U Chetty; A P Forrest
Journal:  Br Med J (Clin Res Ed)       Date:  1985-02-02

Review 4.  Oestrogen receptors and breast cancer: current status.

Authors:  R A Hawkins; M M Roberts; A P Forrest
Journal:  Br J Surg       Date:  1980-03       Impact factor: 6.939

5.  Quantitative oestradiol receptor values in primary breast cancer and response of metastases to endocrine therapy.

Authors:  F C Campbell; R W Blamey; C W Elston; A H Morris; R I Nicholson; K Griffiths; J L Haybittle
Journal:  Lancet       Date:  1981-12-12       Impact factor: 79.321

6.  Fine needle aspiration cytology of breast masses: an evaluation of its accuracy and reasons for diagnostic failure.

Authors:  J J Patel; P C Gartell; J A Smallwood; A Herbert; G Royle; R Buchanan; I Taylor
Journal:  Ann R Coll Surg Engl       Date:  1987-07       Impact factor: 1.891

7.  Comparison of mastectomy with tamoxifen for treating elderly patients with operable breast cancer.

Authors:  J F Robertson; J H Todd; I O Ellis; C W Elston; R W Blamey
Journal:  BMJ       Date:  1988 Aug 20-27

8.  Prediction of endocrine response in breast cancer by immunocytochemical detection of oestrogen receptor in fine-needle aspirates.

Authors:  R C Coombes; T J Powles; U Berger; P Wilson; R A McClelland; J C Gazet; P A Trott; H T Ford
Journal:  Lancet       Date:  1987-09-26       Impact factor: 79.321

9.  Assessment of a scoring scheme for the preoperative diagnosis of breast lumps.

Authors:  J Smallwood; Y Khong; A Boyd; P Guyer; A Herbert; T Cooke; I Taylor
Journal:  Ann R Coll Surg Engl       Date:  1984-07       Impact factor: 1.891

10.  The cytochemical detection of oestrogen receptors in fine needle aspirates of breast cancer; correlation with biochemical assay and prediction of response to endocrine therapy.

Authors:  R A Hawkins; K Sangster; A Tesdale; P A Levack; E D Anderson; U Chetty; A P Forrest
Journal:  Br J Cancer       Date:  1988-07       Impact factor: 7.640
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  5 in total

1.  Treating elderly patients with breast cancer.

Authors:  K Dookeran; A Stotter; R Windle; R Walker
Journal:  BMJ       Date:  1992-05-23

2.  Determining factors which predict response to primary medical therapy in breast cancer using a single fine needle aspirate with immunocytochemical staining and flow cytometry.

Authors:  I N Fernando; T J Powles; M Dowsett; S Ashley; L McRobert; J Titley; M G Ormerod; N Sacks; M C Nicolson; A Nash
Journal:  Virchows Arch       Date:  1995       Impact factor: 4.064

3.  The differing predictive values of oestrogen receptor assays for large breast cancers.

Authors:  D J Gaskell; R A Hawkins; A L Tesdale; K Sangster; U Chetty; A P Forrest
Journal:  Postgrad Med J       Date:  1992-11       Impact factor: 2.401

4.  pS2 protein: a marker improving prediction of response to neoadjuvant tamoxifen in post-menopausal breast cancer patients.

Authors:  I Soubeyran; N Quénel; J M Coindre; F Bonichon; M Durand; J Wafflart; L Mauriac
Journal:  Br J Cancer       Date:  1996-10       Impact factor: 7.640

5.  Determination of oestrogen responsiveness of breast cancer by competitive reverse transcription-polymerase chain reaction.

Authors:  M Carr; F E May; T W Lennard; B R Westley
Journal:  Br J Cancer       Date:  1995-12       Impact factor: 7.640
  5 in total

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