| Literature DB >> 6850571 |
Abstract
Some new di-n-butyltin and tin(IV) complexes of the type Bu2SnL, Bu2SnL2 and SnL2 (where L = anions of Schiff bases derived from S-substituted dithiocarbazates and fluoro-aniline) have been prepared and screened for their antitumor activity in P 388 Lymphocyte Leukaemia system. These complexes do not show any toxicity at low dose levels and display T/C values in the range 94-124. Di-n-butyltin complex derived from salicylaldehyde-S-methyl dithiocarbazate has been found to be the most active in this series.Entities:
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Year: 1983 PMID： 6850571 DOI： 10.1016/0304-3835(83)90138-6
Source DB: PubMed Journal: Cancer Lett ISSN： 0304-3835 Impact factor: 8.679