Literature DB >> 6849516

Bioavailability of sustained-release theophylline granules in apple sauce in pediatric asthmatic patients.

G Z Lotner, G E Vanderpool, S Carroll, D G Tinkelman, D L Spangler.   

Abstract

To facilitate administration of sustained-release theophylline in pediatric patients fourteen children with asthma were studied using intact capsules versus the granular contents in apple sauce. In a cross-over study during multiple dose intervals the effectiveness of this administration technique was demonstrated for maintaining bioavailability and sustained-release characteristics.

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Year:  1983        PMID: 6849516

Source DB:  PubMed          Journal:  Ann Allergy        ISSN: 0003-4738


  1 in total

Review 1.  A clinical and pharmacokinetic basis for the selection and use of slow release theophylline products.

Authors:  L Hendeles; R P Iafrate; M Weinberger
Journal:  Clin Pharmacokinet       Date:  1984 Mar-Apr       Impact factor: 6.447

  1 in total

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