Literature DB >> 6846841

Simultaneous determination of tryptophan and its metabolites in mouse brain by high-performance liquid chromatography with fluorometric detection.

J Yamada, Y Sugimoto, K Horisaka.   

Abstract

A new method for the determination of tryptophan and its metabolites in a single mouse brain using high-performance liquid chromatography (HPLC) with fluorometric detection is described. Tryptophan, serotonin, 5-hydroxyindoleacetic acid, indoleacetic acid, and tryptophol were clearly separated by a C8 reverse-phase column. Tissue preparation is performed only to centrifuge homogenates of brain prior to the injection to HPLC. The sensitivity is in the range from 10 to 15 pg.

Entities:  

Mesh：

Substances：

Year:  1983        PMID： 6846841     DOI： 10.1016/0003-2697(83)90577-8

Source DB:  PubMed          Journal:  Anal Biochem        ISSN： 0003-2697            Impact factor:   3.365


  6 in total

1.  Blocking of striated muscle degeneration by serotonin in C. elegans.

Authors:  Maité Carre-Pierrat; Marie-Christine Mariol; Lucie Chambonnier; Aurélie Laugraud; Fabienne Heskia; Jean Giacomotto; Laurent Ségalat
Journal:  J Muscle Res Cell Motil       Date:  2006-06-22       Impact factor: 2.698

2.  Is a serotonergic mechanism involved in 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced appetite suppression in the Sprague-Dawley rat?

Authors:  K Rozman; B Pfeifer; L Kerecsen; R H Alper
Journal:  Arch Toxicol       Date:  1991       Impact factor: 5.153

3.  Tryptophan metabolism in D-galactosamine-induced liver injury.

Authors:  Y Mizoguchi; C Kodama; M Sakai; Y Sakagami; K Kobayashi; S Morisawa; S Yamamoto; J Yamada
Journal:  Gastroenterol Jpn       Date:  1988-10

4.  Comparative toxicity of four chlorinated dibenzo-p-dioxins (CDDs) and their mixture. Part III: Structure-activity relationship with increased plasma tryptophan levels, but no relationship to hepatic ethoxyresorufin o-deethylase activity.

Authors:  L W Weber; M Lebofsky; B U Stahl; A Kettrup; K Rozman
Journal:  Arch Toxicol       Date:  1992       Impact factor: 5.153

5.  Metabolic effects of feeding a high protein/low carbohydrate diet as compared to a low protein/high carbohydrate diet to rainbow troutSalmo gairdneri.

Authors:  M J Walton
Journal:  Fish Physiol Biochem       Date:  1986-01       Impact factor: 2.794

6.  Relationship between acute toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and disturbance of intermediary metabolism in the Long-Evans rat.

Authors:  F Fan; K K Rozman
Journal:  Arch Toxicol       Date:  1994       Impact factor: 5.153
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.