Literature DB >> 684604

Effect of duration of acute spinal cord compression in a new acute cord injury model in the rat.

A S Rivlin, C H Tator.   

Abstract

The effect of duration of acute compression of the spinal cord was assessed in a new model in the rat. The spinal cord was acutely compressed for varying times by a modified aneurysm clip which produced a compression force of 180 grams. The effect of duration of compression was measured by the inclined plane method of assessing the animals' clinical performance. The results showed a linear relationship between log compression time and clinical performance. Thus, the clinical effect of acute compression of the spinal cord injury is inversely related to duration of compression time and the relationship has been precisely quantified. These results suggest that persisting compression should be relieved as soon as possible in order to improve recovery.

Entities:  

Mesh：

Year:  1978        PMID： 684604

Source DB:  PubMed          Journal:  Surg Neurol        ISSN： 0090-3019


  88 in total

1.  Prevention of spinal cord injury with time-frequency analysis of evoked potentials: an experimental study.

Authors:  Y Hu; K D Luk; W W Lu; A Holmes; J C Leong
Journal:  J Neurol Neurosurg Psychiatry       Date:  2001-12       Impact factor: 10.154

2.  AMP-activated protein kinase-dependent induction of autophagy by erythropoietin protects against spinal cord injury in rats.

Authors:  Peng Wang; Zhong-Dong Xie; Chang-Nan Xie; Chao-Wei Lin; Ji-Li Wang; Li-Na Xuan; Chun-Wu Zhang; Yu Wang; Zhi-Hui Huang; Hong-Lin Teng
Journal:  CNS Neurosci Ther       Date:  2018-04-15       Impact factor: 5.243

3.  The effects of chronic alpha-tocopherol administration on lipid peroxidation in an experimental model of acute spinal cord injury.

Authors:  M Bozbuğa; N Izgi; A Canbolat
Journal:  Neurosurg Rev       Date:  1998       Impact factor: 3.042

Review 4.  Timing of decompressive surgery of spinal cord after traumatic spinal cord injury: an evidence-based examination of pre-clinical and clinical studies.

Authors:  Julio C Furlan; Vanessa Noonan; David W Cadotte; Michael G Fehlings
Journal:  J Neurotrauma       Date:  2010-03-04       Impact factor: 5.269

Review 5.  Biomaterial design strategies for the treatment of spinal cord injuries.

Authors:  Karin S Straley; Cheryl Wong Po Foo; Sarah C Heilshorn
Journal:  J Neurotrauma       Date:  2010-01       Impact factor: 5.269

6.  Neuroprotective effects of ebselen on experimental spinal cord injury in rats.

Authors:  Murat Kalayci; Omer Coskun; Ferda Cagavi; Mehmet Kanter; Ferah Armutcu; Sanser Gul; Bektas Acikgoz
Journal:  Neurochem Res       Date:  2005-03       Impact factor: 3.996

Review 7.  Translational spinal cord injury research: preclinical guidelines and challenges.

Authors:  Paul J Reier; Michael A Lane; Edward D Hall; Y D Teng; Dena R Howland
Journal:  Handb Clin Neurol       Date:  2012

8.  Lipid peroxidation in experimental spinal cord injury: time-level relationship.

Authors:  S Barut; A Canbolat; T Bilge; Y Aydin; B Cokneşeli; U Kaya
Journal:  Neurosurg Rev       Date:  1993       Impact factor: 3.042

9.  Serum leptin levels following acute experimental spinal cord injury.

Authors:  Ali Riza Gezici; Ruchan Ergun; Alper Karakas; Bulent Gunduz
Journal:  J Spinal Cord Med       Date:  2009       Impact factor: 1.985

10.  The effect of duration of compression on lipid peroxidation after experimental spinal cord injury.

Authors:  M Y Kaynar; M Hanci; A Kafadar; K Gümüştaş; A Belce; N Ciplak
Journal:  Neurosurg Rev       Date:  1998       Impact factor: 3.042
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