Literature DB >> 6844921

Human platelet-derived growth factor (PDGF): amino-terminal amino acid sequence.

H N Antoniades, M W Hunkapiller.   

Abstract

Human platelet-derived growth factor (PDGF) obtained from outdated human platelets was subjected to amino-terminal amino acid sequence analysis by automated Edman degradation. Despite the apparent presence of limited proteolytic degradation of the protein derived from this method, the sequence analysis reveals two primary peptide sequences and suggests that active PDGF is composed of two, possibly homologous, peptides linked by a disulfide bond or bonds.

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Year:  1983        PMID： 6844921     DOI： 10.1126/science.6844921

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  22 in total

1.  Recent developments in the structure, function and regulation of platelet-derived growth factor and its receptors.

Authors:  J Tiesman; A Rizzino
Journal:  Cytotechnology       Date:  1989-12       Impact factor: 2.058

2.  Identification of processing events in the synthesis of platelet-derived growth factor-like proteins by human osteosarcoma cells.

Authors:  D T Graves; A J Owen; S R Williams; H N Antoniades
Journal:  Proc Natl Acad Sci U S A       Date:  1986-07       Impact factor: 11.205

3.  Synthesis and secretion of proteins resembling platelet-derived growth factor by human glioblastoma and fibrosarcoma cells in culture.

Authors:  P Pantazis; P G Pelicci; R Dalla-Favera; H N Antoniades
Journal:  Proc Natl Acad Sci U S A       Date:  1985-04       Impact factor: 11.205

4.  [New aspects of the biochemistry and biology of the arterial wall].

Authors:  A J Habenicht; M Goerig; G Schettler
Journal:  Klin Wochenschr       Date:  1984-03-15

5.  A glioma-derived analog to platelet-derived growth factor: demonstration of receptor competing activity and immunological crossreactivity.

Authors:  M Nistér; C H Heldin; A Wasteson; B Westermark
Journal:  Proc Natl Acad Sci U S A       Date:  1984-02       Impact factor: 11.205

6.  Synthesis and secretion of platelet-derived growth factor by human breast cancer cell lines.

Authors:  D A Bronzert; P Pantazis; H N Antoniades; A Kasid; N Davidson; R B Dickson; M E Lippman
Journal:  Proc Natl Acad Sci U S A       Date:  1987-08       Impact factor: 11.205

7.  Platelet-derived growth factor BB enhances osteoclast formation and osteoclast precursor cell chemotaxis.

Authors:  Dian-Qi Li; Qi-Long Wan; Janak L Pathak; Zu-Bing Li
Journal:  J Bone Miner Metab       Date:  2016-09-14       Impact factor: 2.626

8.  Induction of c-sis gene expression and synthesis of platelet-derived growth factor in human myeloid leukemia cells during monocytic differentiation.

Authors:  P Pantazis; E Sariban; D Kufe; H N Antoniades
Journal:  Proc Natl Acad Sci U S A       Date:  1986-09       Impact factor: 11.205

9.  Human leukemia cells synthesize and secrete proteins related to platelet-derived growth factor.

Authors:  P Pantazis; L Lanfrancone; P G Pelicci; R Dalla-Favera; H N Antoniades
Journal:  Proc Natl Acad Sci U S A       Date:  1986-08       Impact factor: 11.205

10.  Anti-peptide antibodies detect oncogene-related proteins in urine.

Authors:  H L Niman; A M Thompson; A Yu; M Markman; J J Willems; K R Herwig; N A Habib; C B Wood; R A Houghten; R A Lerner
Journal:  Proc Natl Acad Sci U S A       Date:  1985-12       Impact factor: 11.205
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