Literature DB >> 6838964

Combined effect of restricted rotational diffusion plus jumps on nuclear magnetic resonance and fluorescence probes of aromatic ring motions in proteins.

R M Levy, R P Sheridan.   

Abstract

A simple model is presented for the motion of phenylalanine and tyrosine rings in proteins. The model consists of restricted rotational diffusion of the rings about the side chain C alpha--C beta (chi 1) and C beta--C gamma (chi 2) axes combined with 180 degree ring flips. The model is used to evaluate order parameters for nuclear magnetic resonance relaxation and fluorescence depolarization probes of aromatic ring motions in proteins. The dependence of the order parameters on orientation in the ring plane is examined and it is demonstrated that in the presence of ring flips, additional ring librations can have a large effect on the probe order parameters.

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Year:  1983        PMID： 6838964      PMCID： PMC1329169          DOI： 10.1016/S0006-3495(83)84422-1

Source DB:  PubMed          Journal:  Biophys J        ISSN： 0006-3495            Impact factor:   4.033


  7 in total

1.  Temperature dependent molecular motion of a tyrosine residue of ferrocytochrome C.

Authors:  I D Campbell; C M Dobson; G R Moore; S J Perkins; R J Williams
Journal:  FEBS Lett       Date:  1976-11       Impact factor: 4.124

2.  Dynamics of the aromatic amino acid residues in the globular conformation of the basic pancreatic trypsin inhibitor (BPTI). I. 1H NMR studies.

Authors:  G Wagner; A DeMarco; K Wüthrich
Journal:  Biophys Struct Mech       Date:  1976-08-23

3.  Subnanosecond motions of tryptophan residues in proteins.

Authors:  I Munro; I Pecht; L Stryer
Journal:  Proc Natl Acad Sci U S A       Date:  1979-01       Impact factor: 11.205

4.  Dipolar NMR relaxation of nonprotonated aromatic carbons in proteins. Structural and dynamical effects.

Authors:  R M Levy; C M Dobson; M Karplus
Journal:  Biophys J       Date:  1982-07       Impact factor: 4.033

5.  Picosecond dynamics of tyrosine side chains in proteins.

Authors:  J A McCammon; P G Wolynes; M Karplus
Journal:  Biochemistry       Date:  1979-03-20       Impact factor: 3.162

6.  Nanosecond segmental mobilities of tryptophan residues in proteins observed by lifetime-resolved fluorescence anisotropies.

Authors:  J R Lakowicz; G Freshwater; G Weber
Journal:  Biophys J       Date:  1980-10       Impact factor: 4.033

7.  Protein dynamics by solid-state NMR: aromatic rings of the coat protein in fd bacteriophage.

Authors:  C M Gall; T A Cross; J A DiVerdi; S J Opella
Journal:  Proc Natl Acad Sci U S A       Date:  1982-01       Impact factor: 11.205
  7 in total
  6 in total

1.  Tryptophan-47 rotational isomerization in variant-3 scorpion neurotoxin. A combination thermodynamic perturbation and umbrella sampling study.

Authors:  C Haydock; J C Sharp; F G Prendergast
Journal:  Biophys J       Date:  1990-06       Impact factor: 4.033

2.  Crankshaft motions of the polypeptide backbone in molecular dynamics simulations of human type-alpha transforming growth factor.

Authors:  A R Fadel; D Q Jin; G T Montelione; R M Levy
Journal:  J Biomol NMR       Date:  1995-09       Impact factor: 2.835

3.  A sharp thermal transition of fast aromatic-ring dynamics in ubiquitin.

Authors:  Vignesh Kasinath; Yinan Fu; Kim A Sharp; A Joshua Wand
Journal:  Angew Chem Int Ed Engl       Date:  2014-12-04       Impact factor: 15.336

4.  NMR relaxation in proteins with fast internal motions and slow conformational exchange: model-free framework and Markov state simulations.

Authors:  Junchao Xia; Nan-jie Deng; Ronald M Levy
Journal:  J Phys Chem B       Date:  2013-05-28       Impact factor: 2.991

5.  ¹³C relaxation experiments for aromatic side chains employing longitudinal- and transverse-relaxation optimized NMR spectroscopy.

Authors:  Ulrich Weininger; Carl Diehl; Mikael Akke
Journal:  J Biomol NMR       Date:  2012-07-03       Impact factor: 2.835

6.  The free energy barrier for arginine gating charge translation is altered by mutations in the voltage sensor domain.

Authors:  Christine S Schwaiger; Sara I Börjesson; Berk Hess; Björn Wallner; Fredrik Elinder; Erik Lindahl
Journal:  PLoS One       Date:  2012-10-19       Impact factor: 3.240
  6 in total

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