Literature DB >> 6838492

The genetics of the sixth and seventh components of complement in the dog: polymorphism, linkage, locus duplication, and silent alleles.

P R Eldridge, M J Hobart, P J Lachmann.   

Abstract

The complement components C6 and C7 exhibit genetic polymorphism in the domestic dog. In the case of C6, there is a single locus with a null allele and two structural alleles; in the case of C7, there are two linked loci, each with three structural alleles. There is a null allele or locus deletion at one of these loci. In all cases, inheritance is autosomal and codominant. The C7 loci are closely linked to each other and to C6. This complex is not close to the dog major histocompatibility complex (MHC) locus.

Entities:  

Mesh:

Substances:

Year:  1983        PMID: 6838492     DOI: 10.1007/bf02395393

Source DB:  PubMed          Journal:  Biochem Genet        ISSN: 0006-2928            Impact factor:   1.890


  12 in total

1.  Nonlinkage between C6 and chromosome 6 markers.

Authors:  J H Olving; B Olaisen; P Teisberg; T Gedde-Dahl; E Thorsby
Journal:  Hum Genet       Date:  1977-06-30       Impact factor: 4.132

2.  Two HLA-linked loci controlling the fourth component of human complement.

Authors:  G J O'Neill; S Y Yang; B Dupont
Journal:  Proc Natl Acad Sci U S A       Date:  1978-10       Impact factor: 11.205

Review 3.  Complement genetics in relation to HLA.

Authors:  P J Lachmann; M J Hobart
Journal:  Br Med Bull       Date:  1978-09       Impact factor: 4.291

4.  Genetic lesion in homozygous alpha thalassaemia (hydrops fetalis).

Authors:  J M Taylor; A Dozy; Y W Kan; H E Varmus; L E Lie-Injo; J Ganesan; D Todd
Journal:  Nature       Date:  1974-10-04       Impact factor: 49.962

5.  The severe form of alpha thalassaemia is caused by a haemoglobin gene deletion.

Authors:  S Ottolenghi; W G Lanyon; J Paul; R Williamson; D J Weatherall; J B Clegg; J Pritchard; S Pootrakul; W H Boon
Journal:  Nature       Date:  1974-10-04       Impact factor: 49.962

6.  Isoelectric focusing in polyacrylamide gel and its application to immunoglobulins.

Authors:  Z L Awdeh; A R Williamson; B A Askonas
Journal:  Nature       Date:  1968-07-06       Impact factor: 49.962

7.  Inherited structural variation and linkage relationships of C7.

Authors:  M J Hobart; V Joysey; P J Lachmann
Journal:  J Immunogenet       Date:  1978-06

8.  Triplicated alpha-globin loci in humans.

Authors:  M Goossens; A M Dozy; S H Embury; Z Zachariades; M G Hadjiminas; G Stamatoyannopoulos; Y W Kan
Journal:  Proc Natl Acad Sci U S A       Date:  1980-01       Impact factor: 11.205

9.  Linkage studies with C6.

Authors:  M J Hobart; P J Cook; P J Lachmann
Journal:  J Immunogenet       Date:  1977-12

10.  A novel alpha-globin gene arrangement in man.

Authors:  D R Higgs; J M Old; L Pressley; J B Clegg; D J Weatherall
Journal:  Nature       Date:  1980-04-17       Impact factor: 49.962

View more
  7 in total

1.  Family study on the polymorphisms of the sixth and seventh components (C6 and C7) of human complement: linkage and haplotype analyses.

Authors:  K Tokunaga; G Dewald; K Omoto; T Juji
Journal:  Am J Hum Genet       Date:  1986-09       Impact factor: 11.025

2.  Genetic polymorphism and linkage of the sixth and seventh complement components (C6 and C7) in the common marmoset.

Authors:  D B Whitehouse
Journal:  Biochem Genet       Date:  1984-02       Impact factor: 1.890

3.  Close linkage between mouse genes determining the two forms of complement component C6 and component C7, and cis action of a C6 regulatory gene.

Authors:  A Orren; M J Hobart; H R Nash; P J Lachmann
Journal:  Immunogenetics       Date:  1985       Impact factor: 2.846

4.  Linkage between complement components 6 and 7 and glutamic pyruvate transaminase in the marsupial Monodelphis domestica.

Authors:  R A van Oorschot; V Birmingham; P A Porter; C M Kammerer; J L VandeBerg
Journal:  Biochem Genet       Date:  1993-06       Impact factor: 1.890

5.  Does the mouse C4-binding protein gene (C4BP) map in the H-2 region?

Authors:  S Rodríguez de Córdoba; A Ferreira; P Rubinstein
Journal:  Immunogenetics       Date:  1985       Impact factor: 2.846

6.  Genetic polymorphism of the sixth component of complement (C6) in mice.

Authors:  J I Hayakawa; H Nikaido; T Koizumi
Journal:  Immunogenetics       Date:  1984       Impact factor: 2.846

7.  Human genes for three complement components that regulate the activation of C3 are tightly linked.

Authors:  S Rodriguez de Cordoba; D M Lublin; P Rubinstein; J P Atkinson
Journal:  J Exp Med       Date:  1985-05-01       Impact factor: 14.307

  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.