Literature DB >> 6833379

The protein responsible for the repeating structure of cytoplasmic poly(A)-ribonucleoprotein.

B W Baer, R D Kornberg.   

Abstract

A 75,000-dalton protein has been purified approximately 1,000-fold from rat liver, based on its capacity to organize poly(A) in a 27-residue repeating structure. This protein may be identified with the major polypeptide component of cytoplasmic poly(A)-ribonucleoprotein (RNP) previously described. The poly(A)-organizing activity of the protein is detected only in cytoplasmic fractions. Upon nuclease digestion of the 75,000-dalton protein-poly(A) complex, monomers, and higher multimers of RNP subunits can be resolved in a sucrose gradient. The sedimentation rate of the monomer is compatible with a composition of one 75,000-dalton protein molecule and one 27-residue segment of poly(A).

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Year:  1983        PMID： 6833379      PMCID： PMC2112416          DOI： 10.1083/jcb.96.3.717

Source DB:  PubMed          Journal:  J Cell Biol        ISSN： 0021-9525            Impact factor:   10.539


  16 in total

1.  Chain length determination of small double- and single-stranded DNA molecules by polyacrylamide gel electrophoresis.

Authors:  T Maniatis; A Jeffrey; H van deSande
Journal:  Biochemistry       Date:  1975-08-26       Impact factor: 3.162

2.  Ribonucleoprotein organization of polyadenylate sequences in HeLa cell heterogeneous nuclear RNA.

Authors:  V M Kish; T Pederson
Journal:  J Mol Biol       Date:  1975-06-25       Impact factor: 5.469

3.  Electron microscopy of defined lengths of chromatin.

Authors:  J T Finch; M Noll; R D Kornberg
Journal:  Proc Natl Acad Sci U S A       Date:  1975-09       Impact factor: 11.205

4.  Rat liver soluble nuclear and cytoplasmic proteins with high affinity to polynucleotides.

Authors:  A Schweiger; G Mazur
Journal:  FEBS Lett       Date:  1975-12-01       Impact factor: 4.124

5.  Nuclear ribonucleoprotein complexes containing polyadenylate from mouse ascites cells.

Authors:  T J Quinlan; P B Billings; T E Martin
Journal:  Proc Natl Acad Sci U S A       Date:  1974-07       Impact factor: 11.205

6.  A particle associated with the polyadenylate segment in mammalian messenger RNA.

Authors:  S W Kwan; G Brawerman
Journal:  Proc Natl Acad Sci U S A       Date:  1972-11       Impact factor: 11.205

7.  The duck-globin messenger-ribonucleoprotein complex. Resistance to high ionic strength, particle gel electrophoresis, composition and visualisation by dark-field electron microscopy.

Authors:  C Morel; E S Gander; M Herzberg; J Dubochet; K Scherrer
Journal:  Eur J Biochem       Date:  1973-07-16

8.  Isolation of messenger ribonucleoproteins from mammalian cells.

Authors:  U Lindberg; B Sundquist
Journal:  J Mol Biol       Date:  1974-06-25       Impact factor: 5.469

9.  Characterization of the association of specific proteins with messenger ribonucleic acid.

Authors:  A Barrieux; H A Ingraham; S Nystul; M G Rosenfeld
Journal:  Biochemistry       Date:  1976-08-10       Impact factor: 3.162

10.  Ribonucleoprotein particles containing heterogeneous nuclear RNA in the cellular slime mold Dictyostelium discoideum.

Authors:  R A Firtel; T Pederson
Journal:  Proc Natl Acad Sci U S A       Date:  1975-01       Impact factor: 11.205
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  66 in total

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Authors:  J E Knight; E N Narus; S L Martin; A Jacobson; B M Barnes; B B Boyer
Journal:  Mol Cell Biol       Date:  2000-09       Impact factor: 4.272

2.  Positive and negative regulation of poly(A) nuclease.

Authors:  David A Mangus; Matthew C Evans; Nathan S Agrin; Mandy Smith; Preetam Gongidi; Allan Jacobson
Journal:  Mol Cell Biol       Date:  2004-06       Impact factor: 4.272

Review 3.  Tales of Detailed Poly(A) Tails.

Authors:  Angela L Nicholson; Amy E Pasquinelli
Journal:  Trends Cell Biol       Date:  2018-11-29       Impact factor: 20.808

4.  Poly(A)-binding protein facilitates translation of an uncapped/nonpolyadenylated viral RNA by binding to the 3' untranslated region.

Authors:  Hiro-Oki Iwakawa; Yuri Tajima; Takako Taniguchi; Masanori Kaido; Kazuyuki Mise; Yukihide Tomari; Hisaaki Taniguchi; Tetsuro Okuno
Journal:  J Virol       Date:  2012-05-16       Impact factor: 5.103

5.  An acidic protein, YBAP1, mediates the release of YB-1 from mRNA and relieves the translational repression activity of YB-1.

Authors:  Ken Matsumoto; Kimio J Tanaka; Masafumi Tsujimoto
Journal:  Mol Cell Biol       Date:  2005-03       Impact factor: 4.272

6.  Dual interactions of the translational repressor Paip2 with poly(A) binding protein.

Authors:  K Khaleghpour; A Kahvejian; G De Crescenzo; G Roy; Y V Svitkin; H Imataka; M O'Connor-McCourt; N Sonenberg
Journal:  Mol Cell Biol       Date:  2001-08       Impact factor: 4.272

7.  Gene and genon concept: coding versus regulation. A conceptual and information-theoretic analysis of genetic storage and expression in the light of modern molecular biology.

Authors:  Klaus Scherrer; Jürgen Jost
Journal:  Theory Biosci       Date:  2007-09-22       Impact factor: 1.919

8.  Uridylation by TUT4 and TUT7 marks mRNA for degradation.

Authors:  Jaechul Lim; Minju Ha; Hyeshik Chang; S Chul Kwon; Dhirendra K Simanshu; Dinshaw J Patel; V Narry Kim
Journal:  Cell       Date:  2014-12-04       Impact factor: 41.582

9.  RNA-binding properties of a translational activator, the adenovirus L4 100-kilodalton protein.

Authors:  D Riley; S J Flint
Journal:  J Virol       Date:  1993-06       Impact factor: 5.103

10.  mRNA polyadenylate-binding protein: gene isolation and sequencing and identification of a ribonucleoprotein consensus sequence.

Authors:  S A Adam; T Nakagawa; M S Swanson; T K Woodruff; G Dreyfuss
Journal:  Mol Cell Biol       Date:  1986-08       Impact factor: 4.272
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