Literature DB >> 6833143

Studies on biosynthesis of pentalenolactone. V isolation of deoxypentalenylglucuron.

S Takahashi, M Takeuchi, M Arai, H Seto, N Otake.   

Abstract

Deoxypentalenylglucuron was isolated from the culture broths of three different strains, such as Streptomyces omiyaensis, S. albofaciens and S. viridifaciens. The structure of deoxypentalenylglucuron has been determined by 1H and 13C NMR, mass spectroscopy and by chemical correlation to be an oxidation product of pentalenene 1. Deoxypentalenylglucuron (1) has some antitumor activity against Sarcoma 180 in mice.

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Year:  1983        PMID： 6833143     DOI： 10.7164/antibiotics.36.226

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  14 in total

1.  Genome mining in streptomyces. Discovery of an unprecedented P450-catalyzed oxidative rearrangement that is the final step in the biosynthesis of pentalenolactone.

Authors:  Dongqing Zhu; Myung-Ji Seo; Haruo Ikeda; David E Cane
Journal:  J Am Chem Soc       Date:  2011-02-01       Impact factor: 15.419

2.  Pentalenolactone biosynthesis: Molecular cloning and assignment of biochemical function to PtlF, a short-chain dehydrogenase from Streptomyces avermitilis, and identification of a new biosynthetic intermediate.

Authors:  Zheng You; Satoshi Omura; Haruo Ikeda; David E Cane
Journal:  Arch Biochem Biophys       Date:  2006-11-22       Impact factor: 4.013

Review 3.  A comprehensive review of glycosylated bacterial natural products.

Authors:  Sherif I Elshahawi; Khaled A Shaaban; Madan K Kharel; Jon S Thorson
Journal:  Chem Soc Rev       Date:  2015-11-07       Impact factor: 54.564

4.  A gene cluster for biosynthesis of the sesquiterpenoid antibiotic pentalenolactone in Streptomyces avermitilis.

Authors:  Charles N Tetzlaff; Zheng You; David E Cane; Satoshi Takamatsu; Satoshi Omura; Haruo Ikeda
Journal:  Biochemistry       Date:  2006-05-16       Impact factor: 3.162

5.  Pentalenolactone biosynthesis. Molecular cloning and assignment of biochemical function to PtlI, a cytochrome P450 of Streptomyces avermitilis.

Authors:  Richard Quaderer; Satoshi Omura; Haruo Ikeda; David E Cane
Journal:  J Am Chem Soc       Date:  2006-10-11       Impact factor: 15.419

Review 6.  Endophytic bacteria: a new source of bioactive compounds.

Authors:  Monika Singh; Ajay Kumar; Ritu Singh; Kapil Deo Pandey
Journal:  3 Biotech       Date:  2017-09-14       Impact factor: 2.406

7.  Terpene synthases are widely distributed in bacteria.

Authors:  Yuuki Yamada; Tomohisa Kuzuyama; Mamoru Komatsu; Kazuo Shin-Ya; Satoshi Omura; David E Cane; Haruo Ikeda
Journal:  Proc Natl Acad Sci U S A       Date:  2014-12-22       Impact factor: 11.205

8.  Genome mining in Streptomyces. Elucidation of the role of Baeyer-Villiger monooxygenases and non-heme iron-dependent dehydrogenase/oxygenases in the final steps of the biosynthesis of pentalenolactone and neopentalenolactone.

Authors:  Myung-Ji Seo; Dongqing Zhu; Saori Endo; Haruo Ikeda; David E Cane
Journal:  Biochemistry       Date:  2011-02-08       Impact factor: 3.162

9.  Crystal structure of the non-heme iron dioxygenase PtlH in pentalenolactone biosynthesis.

Authors:  Zheng You; Satoshi Omura; Haruo Ikeda; David E Cane; Gerwald Jogl
Journal:  J Biol Chem       Date:  2007-10-16       Impact factor: 5.157

10.  Genome mining in Streptomyces avermitilis: A biochemical Baeyer-Villiger reaction and discovery of a new branch of the pentalenolactone family tree.

Authors:  Jiaoyang Jiang; Charles N Tetzlaff; Satoshi Takamatsu; Masato Iwatsuki; Mamoru Komatsu; Haruo Ikeda; David E Cane
Journal:  Biochemistry       Date:  2009-07-14       Impact factor: 3.162
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