Literature DB >> 6832327

Predominant expression of zeta and epsilon globin genes in human leukemia K-562(S6) variant cell line.

R Gambari, G Raschellà, R Biagini, M Tripodi, M G Farace, A Romeo, A Fantoni.   

Abstract

In the human leukemia K-562(S6) cell line (a) the accumulation of alpha-globin chains is low or absent, (b) zeta-globin gene expression is correlated with expression of epsilon-chains and (c) the genes responsible for the terminal cell division are not operated within 8-12 cell cycles, while K-562(S6) cells are fully induced to erythroid differentiation.

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Year:  1983        PMID： 6832327     DOI： 10.1007/bf01963156

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  10 in total

1.  Two new haemoglobin variants in a very young human embryo.

Authors:  E R HUEHNS; F V FLYNN; E A BUTLER; G H BEAVEN
Journal:  Nature       Date:  1961-02-11       Impact factor: 49.962

2.  K562 human leukaemic cells synthesise embryonic haemoglobin in response to haemin.

Authors:  T R Rutherford; J B Clegg; D J Weatherall
Journal:  Nature       Date:  1979-07-12       Impact factor: 49.962

3.  Effects of sodium butyrate on human chronic myelogenous leukaemia cell line K562.

Authors:  C B Lozzio; B B Lozzio; E A Machado; J E Fuhr; S V Lair; E G Bamberger
Journal:  Nature       Date:  1979-10-25       Impact factor: 49.962

Review 4.  Developmental biology of human hemoglobins.

Authors:  W G Wood; J B Clegg; D J Weatherall
Journal:  Prog Hematol       Date:  1977

5.  Hemoglobin expression in clones of K562 cell line.

Authors:  U Testa; W Vainchenker; Y Beuzard; P Rouyer-Fessard; A Guerrasio; M Titeux; P Lapotre; J Bouguet; J Breton-Gorius; J Rosa
Journal:  Eur J Biochem       Date:  1982-01

6.  Embryonic-fetal erythroid characteristics of a human leukemic cell line.

Authors:  E J Benz; M J Murnane; B L Tonkonow; B W Berman; E M Mazur; C Cavallesco; T Jenko; E L Snyder; B G Forget; R Hoffman
Journal:  Proc Natl Acad Sci U S A       Date:  1980-06       Impact factor: 11.205

7.  Tumor promoter-mediated inhibition of cell differentiation: suppression of the expression of erythroid functions in murine erythroleukemia cells.

Authors:  E Fibach; R Gambari; P A Shaw; G Maniatis; R C Reuben; S Sassa; R A Rifkind; P A Marks
Journal:  Proc Natl Acad Sci U S A       Date:  1979-04       Impact factor: 11.205

Review 8.  Embryonic hemoglobins in man and other mammals.

Authors:  A Fantoni; M G Farace; R Gambari
Journal:  Blood       Date:  1981-04       Impact factor: 22.113

9.  Differential expression of the globin genes in human leukemia K562(S) cells induced to differentiate by hemin or butyric acid.

Authors:  L Cioe; A McNab; H R Hubbell; P Meo; P Curtis; G Rovera
Journal:  Cancer Res       Date:  1981-01       Impact factor: 12.701

10.  Embryonic erythroid differentiation in the human leukemic cell line K562.

Authors:  T Rutherford; J B Clegg; D R Higgs; R W Jones; J Thompson; D J Weatherall
Journal:  Proc Natl Acad Sci U S A       Date:  1981-01       Impact factor: 11.205
  10 in total
  1 in total

1.  Efficient cell proliferation and predominant accumulation of epsilon-globin mRNA in human leukemic K562 cells which produce mostly Hb Gower 1.

Authors:  R Gambari; F Amelotti; R Piva
Journal:  Experientia       Date:  1985-05-15
  1 in total

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