Literature DB >> 683178

Mutagenic activation of N-hydroxy-2-acetylaminofluorene in the Salmonella test system: the role of deacetylation by liver and kidney fractions from mouse and rat.

H A Schut, P J Wirth, S S Thorgeirsson.   

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Year:  1978        PMID： 683178

Source DB:  PubMed          Journal:  Mol Pharmacol        ISSN： 0026-895X            Impact factor:   4.436


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  9 in total

1.  Gas chromatography-mass spectrometry analysis of tert.-butyldimethylsilyl derivatives of 2-acetylaminofluorene and metabolites in isolated rat hepatocytes.

Authors:  M A Diez Ibañez; M Chessebeuf-Padieu; P Nordmann; P Padieu
Journal:  Cell Biol Toxicol       Date:  1987-09       Impact factor: 6.691

2.  A comparison of the inhibition of deacetylase in primary cultures of rat and human hepatocytes effecting metabolism and DNA-binding of 2-acetylaminofluorene.

Authors:  D K Monteith; S C Strom
Journal:  Cell Biol Toxicol       Date:  1990-07       Impact factor: 6.691

3.  V79 Chinese hamster cells deacetylate trans-N-acetoxy-4-acetylaminostilbene and trans-N-hydroxy-4-acetylaminostilbene to mutagenic and cytotoxic metabolites.

Authors:  H Glatt; F Oesch; H G Neumann
Journal:  Cell Biol Toxicol       Date:  1986-06       Impact factor: 6.691

4.  Effect of acetylated and deacetylated 2-aminofluorene adducts on in vitro DNA synthesis.

Authors:  P D Moore; S D Rabkin; A L Osborn; C M King; B S Strauss
Journal:  Proc Natl Acad Sci U S A       Date:  1982-12       Impact factor: 11.205

5.  Nonrandom binding of the carcinogen N-hydroxy-2-acetylaminofluorene to repetitive sequences of rat liver DNA in vivo.

Authors:  R C Gupta
Journal:  Proc Natl Acad Sci U S A       Date:  1984-11       Impact factor: 11.205

6.  Modulation of genotoxic and cytotoxic effects of aromatic amines in monolayers of rat hepatocytes.

Authors:  J A Holme; E J Søderlund
Journal:  Cell Biol Toxicol       Date:  1984-10       Impact factor: 6.691

7.  Aminofluorene-DNA adduct formation in Salmonella typhimurium exposed to the carcinogen N-hydroxy-2-acetylaminofluorene.

Authors:  D T Beranek; G L White; R H Heflich; F A Beland
Journal:  Proc Natl Acad Sci U S A       Date:  1982-09       Impact factor: 11.205

8.  Metabolic activation of 2-acetylaminofluorene by isolated rat liver cells. Involvement of different metabolites causing DNA-repair and bacterial mutagenesis.

Authors:  R M Brouns; R P Bos; R von Doorn; P T Henderson
Journal:  Arch Toxicol       Date:  1980-05       Impact factor: 5.153

9.  Genotoxicity of N-acetylarylamines in the salmonella/hepatocyte system.

Authors:  S S Thorgeirsson; L C Erickson; C L Smith; I B Glowinski
Journal:  Environ Health Perspect       Date:  1983-03       Impact factor: 9.031
  9 in total

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