Literature DB >> 6825773

Elimination kinetics of iopamidol, a new water soluble nonionic radiographic contrast medium, analyzed by radioactivation.

O Muratore, S Saitta, G Mallarini, P Corvisiero, M Sanzone.   

Abstract

We have studied the elimination kinetics of iopamidol employing radioactivation and radiochemical separation. This method offers the advantage of guaranteeing absolutely no interference by radiation with tissue distribution or elimination kinetics of the analyzed compound. Our results show that iopamidol does not cross the blood-brain barrier, has no effect on thyroid iodine uptake and does not accumulate in the liver.

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Year:  1983        PMID： 6825773     DOI： 10.1007/bf01960664

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  9 in total

1.  [Complications of water-soluble iodized contrast media. Pathogenesis of complications in relation to the severity of the manifestations. Types of reactions].

Authors:  G F Leroux
Journal:  J Radiol Electrol Med Nucl       Date:  1975

2.  RED CELL AGGREGATION FROM CONCENTRATED SALINE AND ANGIOGRAPHIC MEDIA.

Authors:  M W MEYER; R C READ
Journal:  Radiology       Date:  1964-04       Impact factor: 11.105

3.  Neurotoxicity of X-ray contrast media. Relation to lipid solubility and blood-brain barrier permeability.

Authors:  S I Rapoport; H Levitan
Journal:  Am J Roentgenol Radium Ther Nucl Med       Date:  1974-09

Review 4.  Basic mechanisms of contrast media reactions. Theoretical and experimental considerations.

Authors:  E C Lasser
Journal:  Radiology       Date:  1968-07       Impact factor: 11.105

5.  Cerebrospinal fluid transfer of contrast material at urography.

Authors:  B L McClennan; J A Becker
Journal:  Am J Roentgenol Radium Ther Nucl Med       Date:  1971-11

6.  Effect of angiocardiography on fluid and electrolyte balance.

Authors:  A R Levin; H Grossman; E T Schubert; P Winchester; A Gilladoga
Journal:  Am J Roentgenol Radium Ther Nucl Med       Date:  1969-04

7.  Contrast agent design. Some aspects on the synthesis of water soluble contrast agents of low osmolality.

Authors:  T Almén
Journal:  J Theor Biol       Date:  1969-08       Impact factor: 2.691

8.  Radiopaque contrast media. XLVI - Preliminary studies of the metabolism of iopamidol in the dog, the rabbit and man.

Authors:  D Pitrè; P Tirone; G Viviani
Journal:  Farmaco Sci       Date:  1980-10

9.  Development, chemistry, and physical properties of iopamidol and its analogues.

Authors:  D Pitrè; E Felder
Journal:  Invest Radiol       Date:  1980 Nov-Dec       Impact factor: 6.016
  9 in total
  1 in total

1.  A method for quantitative measurement of cerebral vascular permeability using X-ray CT and iodinated contrast medium.

Authors:  T Terada; K Nambu; G Hyotani; K Miyamoto; M Tsuura; Y Nakamura; T Nishiguchi; T Itakura; S Hayashi; N Komai
Journal:  Neuroradiology       Date:  1992       Impact factor: 2.804
  1 in total

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