Literature DB >> 6824631

Proton magnetic resonance melting studies of CCGGp, CCGGAp, ACCGGp, CCGGUp, and ACCGGUp.

M Petersheim, D H Turner.   

Abstract

Proton magnetic resonance melting curves are reported for the base and ribose 1' nonexchangeable protons of CCGGp, CCGGAp, ACCGGp, CCGGUp, and ACCGGUp. In general, the double helices melt in a cooperative two-state transition. For CCGGp, CCGGAp, CCGGUp, and ACCGGUp, the 3' ribose exhibits conformational flexibility at lower temperatures than the other ribose residues. For ACCGGp, the 5'-C ribose is the first to exhibit flexibility. The conformations of the 3' terminal bases in CCGGAp and CCGGUp change cooperatively with the double- to single-strand transition, whereas the 5' A of ACCGGp appears to have more conformational freedom.

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Year:  1983        PMID： 6824631     DOI： 10.1021/bi00271a006

Source DB:  PubMed          Journal:  Biochemistry        ISSN： 0006-2960            Impact factor:   3.162


  7 in total

1.  Study by (23)Na-NMR, (1)H-NMR, and ultraviolet spectroscopy of the thermal stability of an 11-basepair oligonucleotide.

Authors:  P Cahen; M Luhmer; C Fontaine; C Morat; J Reisse; K Bartik
Journal:  Biophys J       Date:  2000-02       Impact factor: 4.033

2.  Proton NMR studies on the covalently linked RNA-DNA hybrid r(GCG)d(TATACGC). Assignment of proton resonances by application of the nuclear Overhauser effect.

Authors:  J R Mellema; C A Haasnoot; G A van der Marel; G Wille; C A van Boeckel; J H van Boom; C Altona
Journal:  Nucleic Acids Res       Date:  1983-08-25       Impact factor: 16.971

3.  Nuclear magnetic resonance study of d-TGGCCA in solution.

Authors:  E Guittet; D Piveteau; J Y Lallemand; T Huyn-Dinh; J Igolen
Journal:  Nucleic Acids Res       Date:  1984-07-25       Impact factor: 16.971

4.  Conformational analysis of r(CGCGCG) in aqueous solution: an A-type double helical conformation studied by two-dimensional nuclear Overhauser effect spectroscopy.

Authors:  H P Westerink; G A van der Marel; J H van Boom; C A Haasnoot
Journal:  Nucleic Acids Res       Date:  1984-05-25       Impact factor: 16.971

5.  Synthesis and conformational studies of ribooligonucleotides which contain an alternating C-G sequence and show unusual circular dichroism spectra.

Authors:  S Uesugi; M Ohkubo; E Ohtsuka; M Ikehara; Y Kobayashi; Y Kyogoku
Journal:  Nucleic Acids Res       Date:  1984-10-25       Impact factor: 16.971

6.  Revision of AMBER Torsional Parameters for RNA Improves Free Energy Predictions for Tetramer Duplexes with GC and iGiC Base Pairs.

Authors:  Ilyas Yildirim; Scott D Kennedy; Harry A Stern; James M Hart; Ryszard Kierzek; Douglas H Turner
Journal:  J Chem Theory Comput       Date:  2011-12-01       Impact factor: 6.006

7.  Base-stacking and base-pairing contributions into thermal stability of the DNA double helix.

Authors:  Peter Yakovchuk; Ekaterina Protozanova; Maxim D Frank-Kamenetskii
Journal:  Nucleic Acids Res       Date:  2006-01-31       Impact factor: 16.971
  7 in total

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