Literature DB >> 6824560

Antidepressant drugs, convulsions and epilepsy.

A Richens, S Nawishy, M Trimble.   

Abstract

1 Evidence concerning the convulsant effects of non-monoamine oxidase inhibitor antidepressant drugs has been reviewed. 2 Mianserin is convulsant in therapeutic doses but seizures have not been reported following overdose. 3 The convulsant effects of mianserin are probably no greater than for other non-monoamine oxidase inhibitor antidepressant drugs. 4 Enzyme-inducing anti-epileptic drugs can reduce the peak plasma concentration of mianserin and shorten its elimination half-life, probably by inducing its metabolism.

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Year:  1983        PMID： 6824560      PMCID： PMC1427907          DOI： 10.1111/j.1365-2125.1983.tb05878.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN： 0306-5251            Impact factor:   4.335


  18 in total

1.  Epileptic seizures induced by psychotropic drugs.

Authors:  B K Toone; G W Fenton
Journal:  Psychol Med       Date:  1977-05       Impact factor: 7.723

2.  Epileptic fits as a probable side-effect of amitriptyline. Report of seven cases.

Authors:  T A Betts; P L Kalra; R Cooper; P M Jeavons
Journal:  Lancet       Date:  1968-02-24       Impact factor: 79.321

3.  A correlation of EEG, reticular multiple unit activity and gross behavior following various antidepressant agents in the cat. IV.

Authors:  M B Wallach; W D Winters; A J Mandell; C E Spooner
Journal:  Electroencephalogr Clin Neurophysiol       Date:  1969-12

4.  Clinical and EEG studies of doxepin. An interim report.

Authors:  J Simeon; M Spero; M Fink
Journal:  Psychosomatics       Date:  1969 May-Jun       Impact factor: 2.386

5.  Clinical note: seizures and EEG activation after trimipramine.

Authors:  N J Legg; M Swash
Journal:  Epilepsia       Date:  1974-03       Impact factor: 5.864

6.  EEG activation after intravenous amitriptyline.

Authors:  K Davison
Journal:  Electroencephalogr Clin Neurophysiol       Date:  1965-09

7.  Clinical effects and treatment of imipramine and amitriptyline poisoning in children.

Authors:  C M Steel; J O'Duffy; S S Brown
Journal:  Br Med J       Date:  1967-09-09

8.  Seizure activity in photosensitive baboons following antidepressant drugs and the role of serotoninergic mechanisms.

Authors:  M Trimble; G Anlezark; B Meldrum
Journal:  Psychopharmacology (Berl)       Date:  1977-01-31       Impact factor: 4.530

9.  Amitriptyline and imipramine poisoning in children.

Authors:  K M Goel; R A Shanks
Journal:  Br Med J       Date:  1974-02-16

10.  Iatrogenic epilepsy due to antidepressant drugs.

Authors:  V Dallos; K Heathfield
Journal:  Br Med J       Date:  1969-10-11
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  2 in total

Review 1.  The safety of antidepressants.

Authors:  F de Jonghe; J A Swinkels
Journal:  Drugs       Date:  1992       Impact factor: 9.546

Review 2.  Effects of psychotropic drugs on seizure threshold.

Authors:  Francesco Pisani; Giancarla Oteri; Cinzia Costa; Giorgio Di Raimondo; Raoul Di Perri
Journal:  Drug Saf       Date:  2002       Impact factor: 5.606
  2 in total

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