Literature DB >> 681458

Analysis of the registry of toxic effects of chemical substances (RTECS) files and conversion of the data in these files for input to the environmental chemicals data and information network (ECDIN).

O Nørager, W G Town, J H Petrie.   

Abstract

A data bank for environmental chemicals, ECDIN, is being developed at the Joint Research Centre of the European Communities in cooperation with universities and research institutes in the nine member states as a part of the Environmental Research Programme of the EC. During the pilot phase of the project, data from the Registry of Toxic Effects of Chemical Substances have been incorporated into the data bank. Conversions of the data into ECDIN input format was necessary before inclusion of the toxicity data in ECDIN, and the computer programs used for this format conversion have produced various statistics for the contents of the RTECS files. Analyses of the data in three editions of RTECS are presented.

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Year:  1978        PMID: 681458     DOI: 10.1021/ci60015a005

Source DB:  PubMed          Journal:  J Chem Inf Comput Sci        ISSN: 0095-2338


  7 in total

1.  A novel two-step hierarchical quantitative structure-activity relationship modeling work flow for predicting acute toxicity of chemicals in rodents.

Authors:  Hao Zhu; Lin Ye; Ann Richard; Alexander Golbraikh; Fred A Wright; Ivan Rusyn; Alexander Tropsha
Journal:  Environ Health Perspect       Date:  2009-04-03       Impact factor: 9.031

2.  Kinetic analysis on the skin disposition of cytotoxicity as an index of skin irritation produced by cetylpyridinium chloride: comparison of in vitro data using a three-dimensional cultured human skin model with in vivo results in hairless mice.

Authors:  Satoshi Kano; Kenji Sugibayashi
Journal:  Pharm Res       Date:  2006-02-02       Impact factor: 4.200

3.  Weighted feature significance: a simple, interpretable model of compound toxicity based on the statistical enrichment of structural features.

Authors:  Ruili Huang; Noel Southall; Menghang Xia; Ming-Hsuang Cho; Ajit Jadhav; Dac-Trung Nguyen; James Inglese; Raymond R Tice; Christopher P Austin
Journal:  Toxicol Sci       Date:  2009-10-04       Impact factor: 4.849

4.  The semantic architecture of the World-Wide Molecular Matrix (WWMM).

Authors:  Peter Murray-Rust; Sam E Adams; Jim Downing; Joe A Townsend; Yong Zhang
Journal:  J Cheminform       Date:  2011-10-14       Impact factor: 5.514

5.  Caffeine and sleep-deprivation mediated changes in open-field behaviours, stress response and antioxidant status in mice.

Authors:  J Olakunle Onaolapo; Y Adejoke Onaolapo; A Moses Akanmu; Gbola Olayiwola
Journal:  Sleep Sci       Date:  2016-11-12

6.  Structure-activity models of oral clearance, cytotoxicity, and LD50: a screen for promising anticancer compounds.

Authors:  John C Boik; Robert A Newman
Journal:  BMC Pharmacol       Date:  2008-06-13

7.  Are empty methadone bottles empty? An analytic study.

Authors:  Gaël Dupuy; Lia Cavalcanti; Emmanuel Bourgogne; Clara Brichant-Petitjean; Léon Gomberoff; Vanessa Bloch; Frank Bellivier; Jean-Pierre Lépine; Olivier Laprévote; Florence Vorspan
Journal:  Harm Reduct J       Date:  2014-07-02
  7 in total

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