Literature DB >> 6813189

A study of rDNA magnification phenomenon in a repair-recombination deficient mutant of Drosophila melanogaster.

L C Polito, D Cavaliere, A Zazo, M Furia.   

Abstract

The rDNA magnification process consists of a rapid and inheritable rDNA increase occurring in bobbed males: in a few generations the bb loci acquire the wild-type rDNA value and reach a bb+ phenotype.--We have analyzed the rDNA magnification process in the repair-recombination-deficient mutant mei9a, both at the phenotypical and rDNA content levels. In mei9a bb double mutants the recovery of bb+ phenotype is strongly disturbed and the rDNA redundancy value fails to reach the wild-type level. The strong effect of this meiotic mutation on rDNA magnification suggests a close relationship between this phenomenon and the repair-recombination processes.

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Year:  1982        PMID: 6813189      PMCID: PMC1201923     

Source DB:  PubMed          Journal:  Genetics        ISSN: 0016-6731            Impact factor:   4.562


  8 in total

1.  Patterns of reversion to bobbed condition of magnified bobbed loci in D. melanogaster.

Authors:  E Boncinelli; M Furia
Journal:  Mol Gen Genet       Date:  1979-10-02

2.  Crossing-over between X AND Y chromosomes during ribosomal DNA magnification in Drosophila melanogaster.

Authors:  F Ritossa
Journal:  Proc Natl Acad Sci U S A       Date:  1973-07       Impact factor: 11.205

3.  Exchanges at the bobbed locus of Drosophila melanogaster.

Authors:  A Schalet
Journal:  Genetics       Date:  1969-09       Impact factor: 4.562

4.  Increase of rDNA redundancy in bb females of Drosophila melanogaster.

Authors:  S Gargano; F Graziani
Journal:  Mol Gen Genet       Date:  1976-06-15

5.  rDNA magnification at the bobbed locus of the Y chromosome in Drosophila melanogaster.

Authors:  E Boncinelli; F Graziani; L Polito; C Malva; F Ritossa
Journal:  Cell Differ       Date:  1972-06

6.  Genetic analysis of sex chromosomal meiotic mutants in Drosophilia melanogaster.

Authors:  B S Baker; A T Carpenter
Journal:  Genetics       Date:  1972-06       Impact factor: 4.562

7.  The mei-9 alpha mutant of Drosophila melanogaster increases mutagen sensitivity and decreases excision repair.

Authors:  J B Boyd; M D Golino; R B Setlow
Journal:  Genetics       Date:  1976-11       Impact factor: 4.562

8.  Genetic controls of meiotic recombination and somatic DNA metabolism in Drosophila melanogaster.

Authors:  B S Baker; J B Boyd; A T Carpenter; M M Green; T D Nguyen; P Ripoll; P D Smith
Journal:  Proc Natl Acad Sci U S A       Date:  1976-11       Impact factor: 11.205

  8 in total
  2 in total

1.  Differential magnification of rDNA gene types in bobbed mutants of Drosophila melanogaster.

Authors:  R Terracol
Journal:  Mol Gen Genet       Date:  1987-06

2.  Autosomal modifiers of the bobbed phenotype are a major component of the rDNA magnification paradox in Drosophila melanogaster.

Authors:  C H Marcus; A E Zitron; D A Wright; R S Hawley
Journal:  Genetics       Date:  1986-06       Impact factor: 4.562

  2 in total

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