Literature DB >> 6812023

Periodicity in the length of 3'-poly(A) tails from native globin mRNA of rabbit.

J M Kelly, R A Cox.   

Abstract

Globin mRNA from rabbit reticulocytes was labelled at the 3'-end with [5'-32P]pCp by T4 RNA ligase. The 3'-poly(A) tail was released by digestion of mRNA with T1 ribonuclease and its size distribution determined by gel electrophoresis and autoradiography. The length of the 3'-poly(A) tails varied from about 15-150 residues, but the size distribution exhibited peaks in the abundance of poly(A) species at intervals of approx. 25 residues. This periodicity appears to reflect the manner in which proteins bind to the 3'-poly(A) tail. The function of such regular interactions may be to control mRNA breakdown in the cytoplasm.

Entities:  

Mesh：

Substances：

Year:  1982        PMID： 6812023      PMCID： PMC320791          DOI： 10.1093/nar/10.14.4173

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  14 in total

1.  Direct chemical method for sequencing RNA.

Authors:  D A Peattie
Journal:  Proc Natl Acad Sci U S A       Date:  1979-04       Impact factor: 11.205

2.  Characteristics of the polyadenylic acid segment associated with messenger ribonucleic acid in mouse sarcoma 180 ascites cells.

Authors:  J Mendecki; S Y Lee; G Brawerman
Journal:  Biochemistry       Date:  1972-02-29       Impact factor: 3.162

3.  Polyadenylic acid segment in mRNA becomes shorter with age.

Authors:  D Sheiness; J E Darnell
Journal:  Nat New Biol       Date:  1973-02-28

4.  A protein of molecular weight 78,000 bound to the polyadenylate region of eukaryotic messenger RNAs.

Authors:  G Blobel
Journal:  Proc Natl Acad Sci U S A       Date:  1973-03       Impact factor: 11.205

5.  Characterization of polypeptides associated with messenger RNA and its polyadenylate segment in Ehrlich ascites messenger ribonucleoprotein.

Authors:  W R Jeffery
Journal:  J Biol Chem       Date:  1977-05-25       Impact factor: 5.157

6.  Poly(A) polymerase and poly(A)-specific mRNA binding protein are antigenically related.

Authors:  K M Rose; S T Jacob; A Kumar
Journal:  Nature       Date:  1979-05-17       Impact factor: 49.962

7.  Complete 3' noncoding region sequences of rabbit and human beta-globin messenger RNAs.

Authors:  N J Proudfoot
Journal:  Cell       Date:  1977-04       Impact factor: 41.582

8.  Repeating structure of cytoplasmic poly(A)-ribonucleoprotein.

Authors:  B W Baer; R D Kornberg
Journal:  Proc Natl Acad Sci U S A       Date:  1980-04       Impact factor: 11.205

9.  Nucleotide sequence of the 3' terminal third of rabbit alpha-globin messenger RNA: comparison with human alpha-globin messenger RNA.

Authors:  N J Proudfoot; S Gillam; M Smith; J I Longley
Journal:  Cell       Date:  1977-08       Impact factor: 41.582

10.  Control of breakdown of the polyadenylate sequence in mammalian polyribosomes: role of poly(adenylic acid)-protein interactions.

Authors:  I E Bergmann; G Brawerman
Journal:  Biochemistry       Date:  1977-01-25       Impact factor: 3.162
View more
  3 in total

1.  Nucleotide sequence of small polyadenylated B2 RNA.

Authors:  D A Kramerov; S V Tillib; A P Ryskov; G P Georgiev
Journal:  Nucleic Acids Res       Date:  1985-09-25       Impact factor: 16.971

2.  The vasopressin mRNA poly(A) tract is unusually long and increases during stimulation of vasopressin gene expression in vivo.

Authors:  E J Carrazana; K B Pasieka; J A Majzoub
Journal:  Mol Cell Biol       Date:  1988-06       Impact factor: 4.272

Review 3.  Nonviral Delivery Systems of mRNA Vaccines for Cancer Gene Therapy.

Authors:  Yusi Wang; Rui Zhang; Lin Tang; Li Yang
Journal:  Pharmaceutics       Date:  2022-02-25       Impact factor: 6.321
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.