Literature DB >> 6806905

Metabolism of 2,4',5-trichlorobiphenyl by the mercapturic acid pathway.

J E Bakke, A L Bergman, G L Larsen.   

Abstract

Carbon-14-labeled 2,4',5-trichlorobiphenyl was found to be metabolized by the mercapturic acid pathway to metabolites that are excreted in bile. About 57 percent of the carbon-14 was excreted in the bile; 30 to 35 percent was present as mercapturic acid pathway metabolites. Mercapturic acid was also isolated from the urine (0.3 percent of the dose).

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Year:  1982        PMID: 6806905     DOI: 10.1126/science.6806905

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  18 in total

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4.  Maternal and cord serum exposure to PCB and DDE methyl sulfone metabolites in eastern Slovakia.

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6.  Elimination of inhaled 3,3'-dichlorobiphenyl and the formation of the 4-hydroxylated metabolite.

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Review 9.  Occurrence and distribution of PCB metabolites in blood and their potential health effects in humans: a review.

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10.  Identification of sulfated metabolites of 4-chlorobiphenyl (PCB3) in the serum and urine of male rats.

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