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Literature DB >> 6805467

Classification and genetic expression of Wistar rats with high and low hepatic microsomal UDP-glucuronosyltransferase activity towards androsterone.

Abstract

Male and female Wistar rats with high and low hepatic microsomal UDP-glucuronosyltransferase activity towards androsterone were classified by partial hepatectomy. The breeding experiments between the classified high-activity and low-activity rats show that the genetic expression of the high transferase activity is inherited in an autosomal dominant fashion.

Entities: Chemical Species

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Year: 1982 PMID： 6805467 PMCID： PMC1158087 DOI： 10.1042/bj2020171

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

12 in total

1. Discontinuous variation in hepatic uridine diphosphate glucuronyltransferase toward androsterone in Wistar rats. A regulatory factor for in vivo metabolism of androsterone.

Authors: M Matsui; M Hakozaki
Journal: Biochem Pharmacol Date: 1979 Impact factor: 5.858

2. Variations in biliary metabolites of androsterone in female rats.

Authors: M Matsui; M Hakozaki
Journal: J Steroid Biochem Date: 1977-04 Impact factor: 4.292

3. Reactivation of a pure defective UDP-glucuronyltransferase from homozygous Gunn rat liver.

Authors: P J Weatherill; B Burchell
Journal: FEBS Lett Date: 1978-03-15 Impact factor: 4.124

4. Kinetic properties of microsomal UDP-glucuronyltransferase. Evidence for cooperative kinetics and activation by UDP-N-acetylglucosamine.

Authors: D A Vessey; J Goldenberg; D Zakim
Journal: Biochim Biophys Acta Date: 1973-05-05

5. Hepatic UDP-glucuronyltransferase in Wistar and Gunn rats--in vitro activation by diethylnitrosamine.

Authors: I Stevenson; D Greenwood; J McEwen
Journal: Biochem Biophys Res Commun Date: 1968-09-06 Impact factor: 3.575

6. An improved assay for steroid glucuronyltransferase in rat liver microsomes.

Authors: G S Rao; G Haueter; M L Rao; H Breuer
Journal: Anal Biochem Date: 1976-07 Impact factor: 3.365

7. UDP-glucuronyltransferase in perfused rat liver and in microsomes: influence of phenobarbital and 3-methylcholanthrene.

Authors: K W Bock; I N White
Journal: Eur J Biochem Date: 1974-08-01

8. Phospholipid content and activity of pure uridine diphosphate-glucuronyltransferase from rat liver.

Authors: B Burchell; T Hallinan
Journal: Biochem J Date: 1978-06-01 Impact factor: 3.857

9. Stimulation of defective Gunn-rat liver uridine diphosphate glucuronyltransferase activity in vitro by alkyl ketones.

Authors: E N Lalani; B Burchell
Journal: Biochem J Date: 1979-03-01 Impact factor: 3.857

10. Genetic regulation of UDP-glucuronosyltransferase induction by polycyclic aromatic compounds in mice. Co-segregation with aryl hydrocarbon (benzo(alpha)pyrene) hydroxylase induction.

Authors: I S Owens
Journal: J Biol Chem Date: 1977-05-10 Impact factor: 5.157

7 in total

1. Genetic deficiency of androsterone UDP-glucuronosyltransferase activity in Wistar rats is due to the loss of enzyme protein.

Authors: M Matsui; F Nagai
Journal: Biochem J Date: 1986-02-15 Impact factor: 3.857

Review 2. Non-invasive molecular imaging of kidney diseases.

Authors: Barbara M Klinkhammer; Twan Lammers; Felix M Mottaghy; Fabian Kiessling; Jürgen Floege; Peter Boor
Journal: Nat Rev Nephrol Date: 2021-06-29 Impact factor: 28.314

3. Isolation of multiple normal and functionally defective forms of uridine diphosphate-glucuronosyltransferase from inbred Gunn rats.

Authors: N Roy Chowdhury; F Gross; A D Moscioni; M Kram; I M Arias; J Roy Chowdhury
Journal: J Clin Invest Date: 1987-02 Impact factor: 14.808

4. Effects of steroid hormones and xenobiotics on the pubertal development of UDP-glucuronosyltransferase activities towards androsterone and 4-nitrophenol in Wistar rats.

Authors: H K Watanabe; M Matsui
Journal: Biochem J Date: 1984-09-01 Impact factor: 3.857

5. Studies on the genetic linkage of bilirubin and androsterone UDP-glucuronyltransferases by cross-breeding of two mutant rat strains.

Authors: F Nagai; H Homma; H Tanase; M Matsui
Journal: Biochem J Date: 1988-06-15 Impact factor: 3.857

6. Developmental alteration of hepatic UDP-glucuronosyltransferase and sulphotransferase towards androsterone and 4-nitrophenol in Wistar rats.

Authors: M Matsui; H K Watanabe
Journal: Biochem J Date: 1982-05-15 Impact factor: 3.857

7. Strain differences in purified rat hepatic 3 alpha-hydroxysteroid UDP-glucuronosyltransferase.

Authors: M D Green; C N Falany; R B Kirkpatrick; T R Tephly
Journal: Biochem J Date: 1985-09-01 Impact factor: 3.857

7 in total