Literature DB >> 6803536

15-Hydroxy-5,8,11,13-eicosatetraenoic acid (15-HETE) formation by rabbit peritoneal tissue.

M Claeys, M C Coene, A G Herman, M Van der Planken, G H Jouvenaz, D H Nugteren.   

Abstract

The capacity of rabbit peritoneal tissue to produce lipoxygenase metabolites from exogenous arachidonic acid has been studied. The lipoxygenase pathway of arachidonic acid in this tissue is mainly directed to 15-HETE. Preliminary experiments with peritoneal macrophages indicate that these cells, just like PMN leukocytes, may contribute to the 15-HETE formation observed in peritoneal tissue.

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Year:  1981        PMID： 6803536     DOI： 10.1007/BF01978754

Source DB:  PubMed          Journal:  Agents Actions        ISSN： 0065-4299


  11 in total

1.  Arachidonate lipoxygenase in blood platelets.

Authors:  D H Nugteren
Journal:  Biochim Biophys Acta       Date:  1975-02-20

2.  Prostaglandin production by cultured mesothelial cells.

Authors:  M C Coene; C Solheid; M Claeys; A G Herman
Journal:  Arch Int Pharmacodyn Ther       Date:  1981-02

3.  Transfomration of arachidonic acid into 12-hydroxy-5,8,10,14-eicosatetraenoic acid by mouse peritoneal macrophages.

Authors:  M Rigaud; J Durand; J C Breton
Journal:  Biochim Biophys Acta       Date:  1979-05-25

4.  Transformation of arachidonic acid and homo-gamma-linolenic acid by rabbit polymorphonuclear leukocytes. Monohydroxy acids from novel lipoxygenases.

Authors:  P Borgeat; M Hamberg; B Samuelsson
Journal:  J Biol Chem       Date:  1976-12-25       Impact factor: 5.157

5.  Arachidonic acid metabolism in polymorphonuclear leukocytes: effects of ionophore A23187.

Authors:  P Borgeat; B Samuelsson
Journal:  Proc Natl Acad Sci U S A       Date:  1979-05       Impact factor: 11.205

6.  Inhibition of leukotriene biosynthesis by the leukocyte product 15-hydroxy-5,8,11,13-eicosatetraenoic acid.

Authors:  J Y Vanderhoek; R W Bryant; J M Bailey
Journal:  J Biol Chem       Date:  1980-11-10       Impact factor: 5.157

7.  Transformation of arachidonic acid by rabbit polymorphonuclear leukocytes. Formation of a novel dihydroxyeicosatetraenoic acid.

Authors:  P Borgeat; B Samuelsson
Journal:  J Biol Chem       Date:  1979-04-25       Impact factor: 5.157

8.  Identification of 15-hydroxy-5,8,11,13-eicosatetraenoic acid (15-HETE) as a major metabolite of arachidonic acid in human lung.

Authors:  M Hamberg; P Hedqvist; K Rådegran
Journal:  Acta Physiol Scand       Date:  1980-10

9.  15-hydroxy-5,8,11,13-eicosatetraenoic acid: A potent and selective inhibitor of platelet lipoxygenase.

Authors:  J Y Vanderhoek; R W Bryant; J M Bailey
Journal:  J Biol Chem       Date:  1980-07-10       Impact factor: 5.157

10.  Prostaglandin endoperoxides. Novel transformations of arachidonic acid in human platelets.

Authors:  M Hamberg; B Samuelsson
Journal:  Proc Natl Acad Sci U S A       Date:  1974-09       Impact factor: 11.205
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