| Literature DB >> 109127 |
M Rigaud, J Durand, J C Breton.
Abstract
Mouse peritoneal macrophages were incubated at 37 degrees C for 30 min with arachidonic acid (all-cis-5,8,11,14-eicosatetraenoic acid). Oxygenation of arachidonic acid in mouse peritoneal macrophages occurs by two major pathways: fatty acid cyclooxygenase and lipoxygenase. The major metabolite of the latter is 12-hydroxy-5,8,10,14-eicosatetraenoic acid which was identified by gas liquid chromatography on high resolution glass capillary column and mass spectrometry.Entities:
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Year: 1979 PMID： 109127 DOI： 10.1016/0005-2760(79)90074-2
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002