Literature DB >> 6802849

Basement membrane (type IV) collagen is a heteropolymer.

B Trüeb, B Gröbli, M Spiess, B F Odermatt, K H Winterhalter.   

Abstract

Type IV collagen was isolated in high yield from bovine kidney cortex. The protein revealed Mr = 380,000 and contained, in a 2:1 ratio, two different disulfide-linked polypeptide chains, C-1 and D-1 (Mr = 125,000). Carboxymethyl-cellulose chromatography before and after reduction proved that the two polypeptide chains are arranged in a single triple helical molecule with the chain composition (C-1)2(D-1). The disulfide bridges appear to be located 180 amino acid residues from the NH2 terminus of the chains.

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Year:  1982        PMID： 6802849

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


  22 in total

1.  A novel chain of basement membrane-associated collagen as revealed by biochemical and immunohistochemical characterizations of the epitope recognized by a monoclonal antibody against human placenta basement membrane collagen.

Authors:  J Kino; E Adachi; T Yoshida; C Asamatsu; K Nakajima; K Yamamoto; T Hayashi
Journal:  Am J Pathol       Date:  1991-04       Impact factor: 4.307

2.  Separation and characterization of two polypeptide chains from the 7S cross-linking domain of basement-membrane (type IV) collagen.

Authors:  R G Qian; R W Glanville
Journal:  Biochem J       Date:  1984-09-01       Impact factor: 3.857

3.  COL4A2 mutations impair COL4A1 and COL4A2 secretion and cause hemorrhagic stroke.

Authors:  Marion Jeanne; Cassandre Labelle-Dumais; Jeff Jorgensen; W Berkeley Kauffman; Grazia M Mancini; Jack Favor; Valerie Valant; Steven M Greenberg; Jonathan Rosand; Douglas B Gould
Journal:  Am J Hum Genet       Date:  2011-12-29       Impact factor: 11.025

Review 4.  Genotype-phenotype correlations in pathology caused by collagen type IV alpha 1 and 2 mutations.

Authors:  Marion Jeanne; Douglas B Gould
Journal:  Matrix Biol       Date:  2016-10-26       Impact factor: 11.583

5.  Monoclonal antibodies to human type IV collagen: useful reagents to demonstrate the heterotrimeric nature of the molecule.

Authors:  B F Odermatt; A B Lang; J R Rüttner; K H Winterhalter; B Trüeb
Journal:  Proc Natl Acad Sci U S A       Date:  1984-12       Impact factor: 11.205

6.  Structural studies of human basement-membrane collagen with the use of a monoclonal antibody.

Authors:  H Dieringer; D W Hollister; R W Glanville; L Y Sakai; K Kühn
Journal:  Biochem J       Date:  1985-04-01       Impact factor: 3.857

7.  Human collagen genes encoding basement membrane alpha 1 (IV) and alpha 2 (IV) chains map to the distal long arm of chromosome 13.

Authors:  C A Griffin; B S Emanuel; J R Hansen; W K Cavenee; J C Myers
Journal:  Proc Natl Acad Sci U S A       Date:  1987-01       Impact factor: 11.205

8.  Assembly of chick and bovine lens-capsule collagen.

Authors:  C M Taylor; M E Grant
Journal:  Biochem J       Date:  1985-03-01       Impact factor: 3.857

9.  Molecular and Genetic Analyses of Collagen Type IV Mutant Mouse Models of Spontaneous Intracerebral Hemorrhage Identify Mechanisms for Stroke Prevention.

Authors:  Marion Jeanne; Jeff Jorgensen; Douglas B Gould
Journal:  Circulation       Date:  2015-03-09       Impact factor: 29.690

10.  Identification of a novel sequence element in the common promoter region of human collagen type IV genes, involved in the regulation of divergent transcription.

Authors:  G Fischer; C Schmidt; J Opitz; Z Cully; K Kühn; E Pöschl
Journal:  Biochem J       Date:  1993-06-15       Impact factor: 3.857
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