Literature DB >> 6799577

Use of monoclonal antibody to increase sensitivity and specificity in quantitative immunodiffusion assays.

L M Glode, R R Montgomery, C G Smith, D B Link.   

Abstract

A mouse monoclonal antibody has been produced which recognizes human liver gamma-cystathionase, Radioiodination of the monoclonal antibody facilitated its use in combination with non-specific precipitating rabbit antisera in classical immunodiffusion assays. The technique may have broad applicability in the detection and quantitation of rare antigens which are difficult to purify but easily recognizable in immunodiffusion assays. It may also be used for the initial detection of monoclonal antibodies to unique antigens of interest.

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Year:  1982        PMID: 6799577     DOI: 10.1016/0022-1759(82)90205-8

Source DB:  PubMed          Journal:  J Immunol Methods        ISSN: 0022-1759            Impact factor:   2.303


  4 in total

1.  Development and characterization of a monoclonal antibody against the tube precipitin antigen of Coccidioides immitis.

Authors:  M J Dolan; R A Cox; V Williams; S Woolley
Journal:  Infect Immun       Date:  1989-04       Impact factor: 3.441

2.  Diagnosis of Bernard-Soulier syndrome and Glanzmann's thrombasthenia with a monoclonal assay on whole blood.

Authors:  R R Montgomery; T J Kunicki; C Taves; D Pidard; M Corcoran
Journal:  J Clin Invest       Date:  1983-02       Impact factor: 14.808

3.  Platelets have more than one binding site for von Willebrand factor.

Authors:  Z M Ruggeri; L De Marco; L Gatti; R Bader; R R Montgomery
Journal:  J Clin Invest       Date:  1983-07       Impact factor: 14.808

4.  Drug-antibody-platelet interaction in quinine- and quinidine-induced thrombocytopenia.

Authors:  D J Christie; R H Aster
Journal:  J Clin Invest       Date:  1982-11       Impact factor: 14.808

  4 in total

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