Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Diagnosis of Bernard-Soulier syndrome and Glanzmann's thrombasthenia with a monoclonal assay on whole blood.

Literature DB >> 6822670

Diagnosis of Bernard-Soulier syndrome and Glanzmann's thrombasthenia with a monoclonal assay on whole blood.

R R Montgomery, T J Kunicki, C Taves, D Pidard, M Corcoran.

Abstract

Two hereditary platelet disorders, Bernard-Soulier syndrome and Glanzmann's thrombasthenia, are characterized by selective deficiencies of platelet membrane glycoproteins. Murine monoclonal antibodies were developed against platelet membrane glycoprotein Ib and against the glycoprotein IIb/IIIa complex. A rapid whole blood assay for the deficiency of these glycoproteins was developed and used to study whole blood samples from six patients with Glanzmann's thrombasthenia and three patients with Bernard-Soulier syndrome. Patients with type I and type II Glanzmann's thrombasthenia were easily detectable with this assay. This permits the diagnosis of these disorders on 200 microliters of whole blood within 2 h of blood sampling.

Entities: Disease Species

Mesh：

Substances：

Year: 1983 PMID： 6822670 PMCID： PMC436878 DOI： 10.1172/jci110780

Source DB: PubMed Journal: J Clin Invest ISSN： 0021-9738 Impact factor: 14.808

13 in total

Review 1. The different glycoprotein abnormalities in thrombasthenic and Bernard-Soulier platelets.

Authors: A T Nurden; J P Caen
Journal: Semin Hematol Date: 1979-07 Impact factor: 3.851

2. An abnormal platelet glycoprotein pattern in three cases of Glanzmann's thrombasthenia.

Authors: A T Nurden; J P Caen
Journal: Br J Haematol Date: 1974-10 Impact factor: 6.998

3. Absence of the platelet receptor for drug-dependent antibodies in the Bernard-Soulier syndrome.

Authors: T J Kunicki; M M Johnson; R H Aster
Journal: J Clin Invest Date: 1978-09 Impact factor: 14.808

4. Bernard-Soulier disease: a study of four patients and their parents.

Authors: J N George; T A Reimann; J L Moake; R K Morgan; P L Cimo; D A Sears
Journal: Br J Haematol Date: 1981-07 Impact factor: 6.998

5. Platelet membrane glycoproteins in thrombasthenia, Bernard-Soulier syndrome, and storage pool disease.

Authors: G A Jamieson; T Okumura; B Fishback; M M Johnson; J J Egan; H J Weiss
Journal: J Lab Clin Med Date: 1979-04

6. Isolation and quantitation of the platelet membrane glycoprotein deficient in thrombasthenia using a monoclonal hybridoma antibody.

Authors: R P McEver; N L Baenziger; P W Majerus
Journal: J Clin Invest Date: 1980-12 Impact factor: 14.808

7. Monoclonal antibodies to von Willebrand's factor: reactivity with porcine and human antigens.

Authors: J A Katzmann; D K Mujwid; R S Miller; D N Fass
Journal: Blood Date: 1981-09 Impact factor: 22.113

8. Characterization of human platelet glycoprotein antigens giving rise to individual immunoprecipitates in crossed-immunoelectrophoresis.

Authors: T J Kunicki; A T Nurden; D Pidard; N R Russell; J P Caen
Journal: Blood Date: 1981-12 Impact factor: 22.113

9. The formation of Ca++-dependent complexes of platelet membrane glycoproteins IIb and IIIa in solution as determined by crossed immunoelectrophoresis.

Authors: T J Kunicki; D Pidard; J P Rosa; A T Nurden
Journal: Blood Date: 1981-08 Impact factor: 22.113

10. Detection and characterization of monoclonal antibodies to platelet membrane proteins.

Authors: P J Newman; R A Kahn; A Hines
Journal: J Cell Biol Date: 1981-07 Impact factor: 10.539

26 in total

1. Dynamic redistribution of major platelet surface receptors after contact-induced platelet activation and spreading. An immunoelectron microscopy study.

Authors: N Kieffer; J Guichard; J Breton-Gorius
Journal: Am J Pathol Date: 1992-01 Impact factor: 4.307

2. Plasma membrane GPIIb/IIIa. Evidence for a cycling receptor pool.

Authors: J D Wencel-Drake
Journal: Am J Pathol Date: 1990-01 Impact factor: 4.307

Review 3. The GPIIb/IIIa (integrin alphaIIbbeta3) odyssey: a technology-driven saga of a receptor with twists, turns, and even a bend.

Authors: Barry S Coller; Sanford J Shattil
Journal: Blood Date: 2008-10-15 Impact factor: 22.113

4. On the association of the platelet-specific alloantigen, Pena, with glycoprotein IIIa. Evidence for heterogeneity of glycoprotein IIIa.

Authors: K Furihata; D J Nugent; A Bissonette; R H Aster; T J Kunicki
Journal: J Clin Invest Date: 1987-12 Impact factor: 14.808

5. Localization of internal pools of membrane glycoproteins involved in platelet adhesive responses.

Authors: J D Wencel-Drake; E F Plow; T J Kunicki; V L Woods; D M Keller; M H Ginsberg
Journal: Am J Pathol Date: 1986-08 Impact factor: 4.307

Review 6. Laboratory investigation of platelet function: a review of methodology.

Authors: D A Yardumian; I J Mackie; S J Machin
Journal: J Clin Pathol Date: 1986-07 Impact factor: 3.411

7. Glycoprotein Ib distribution on the surface of platelets in resting and activation states: an electron microscope study.

Authors: H Suzuki; N Yamamoto; K Tanoue; H Yamazaki
Journal: Histochem J Date: 1987-03

8. Identification and isolation of a platelet GPIb-like protein in human umbilical vein endothelial cells and bovine aortic smooth muscle cells.

Authors: A S Asch; B Adelman; M Fujimoto; R L Nachman
Journal: J Clin Invest Date: 1988-05 Impact factor: 14.808

Review 9. Platelets in allergy. Assays and interpretation.

Authors: M Joseph
Journal: Clin Rev Allergy Date: 1988

10. The phosphoprotein that regulates platelet Ca2+ transport is located on the plasma membrane, controls membrane-associated Ca2(+)-ATPase and is not glycoprotein Ib beta-subunit.

Authors: A Darnanville; R Bredoux; K J Clemetson; N Kieffer; N Bourdeau; S Levy-Toledano; J P Caen; J Enouf
Journal: Biochem J Date: 1991-01-15 Impact factor: 3.857