Literature DB >> 6787645

Increased platelet monoamine oxidase activity in affective disorders.

M A Reveley, V Glover, M Sandler, A Coppen.   

Abstract

Platelet monoamine oxidase activity was determined in 52 unipolar depressive patients, 26 patients with bipolar affective disorder and 48 controls using phenylethylamine as substrate. Unipolar depressive patients of either sex and bipolar depressive women showed significantly higher platelet MAO activity than controls. Women had higher activity than men. Neither age nor serum lithium level correlated with enzyme activity and there was no significant change in activity after the institution of lithium treatment.

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Year:  1981        PMID： 6787645     DOI： 10.1007/BF00422413

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN： 0033-3158            Impact factor:   4.530


  21 in total

1.  CLINICAL TRIAL OF THE TREATMENT OF DEPRESSIVE ILLNESS. REPORT TO THE MEDICAL RESEARCH COUNCIL BY ITS CLINICAL PSYCHIATRY COMMITTEE.

Authors:  M THIERY
Journal:  Br Med J       Date:  1965-04-03

2.  Monoamine oxidase activity in blood platelets from patients with cyclophrenic depressive syndromes.

Authors:  J Landowski; W Lysiak; S Angielski
Journal:  Biochem Med       Date:  1975-12

3.  Reduced MAO activity in first-degree relatives of individuals with bipolar affective disorders. A preliminary report.

Authors:  J F Leckman; E S Gershon; A S Nichols; D L Murphy
Journal:  Arch Gen Psychiatry       Date:  1977-05

4.  Effects of lithium therapy on mao in manic-depressive illness.

Authors:  W H Berrettini; W H Vogel; R K Ladman
Journal:  Am J Psychiatry       Date:  1979-06       Impact factor: 18.112

5.  Ageing, monoamines, and monoamine-oxidase levels.

Authors:  D S Robinson; A Nies; J N Davis; W E Bunney; J M Davis; R W Colburn; H R Bourne; D M Shaw; A J Coppen
Journal:  Lancet       Date:  1972-02-05       Impact factor: 79.321

6.  Reduced monoamine oxidase activity in blood platelets from bipolar depressed patients.

Authors:  D L Murphy; R Weiss
Journal:  Am J Psychiatry       Date:  1972-05       Impact factor: 18.112

7.  Relation of sex and aging to monoamine oxidase activity of human brain, plasma, and platelets.

Authors:  D S Robinson; J M Davis; A Nies; C L Ravaris; D Sylwester
Journal:  Arch Gen Psychiatry       Date:  1971-06

8.  Platelet monoamine oxidase in affective disorders.

Authors:  D J Edwards; D G Spiker; D J Kupfer; G Foster; J F Neil; L Abrams
Journal:  Arch Gen Psychiatry       Date:  1978-12

9.  Increased human platelet monoamine oxidase activity during lithium carbonate therapy.

Authors:  J Bockar; R Roth; G Heninger
Journal:  Life Sci       Date:  1974-12-15       Impact factor: 5.037

Review 10.  Platelet monoamine oxidase activity in schizophrenia: a review of the data.

Authors:  R J Wyatt; S G Potkin; D L Murphy
Journal:  Am J Psychiatry       Date:  1979-04       Impact factor: 18.112
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  1 in total

1.  Lithium alters the stereoselectivity of monoamine oxidase in rat brain.

Authors:  D F Smith
Journal:  J Neural Transm       Date:  1989       Impact factor: 3.575
  1 in total

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