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Literature DB >> 6785799

A preliminary double-blind study on the efficacy of carbamazepine in prophylaxis of manic-depressive illness.

T Okuma, K Inanaga, S Otsuki, K Sarai, R Takahashi, H Hazama, A Mori, S Watanabe.

Abstract

A preliminary double-blind controlled study on the prophylactic effect of carbamazepine on recurrent manic-depressive psychotics was conducted with 22 patients using an inert placebo in ten subjects as a control drug. Carbamazepine in the dosage of 200-600 mg was administered for 1 year. Among the 22 carbamazepine subjects, carbamazepine was found to be effective in 60% of the cases and inert placebo in 22.2% (U-test, P less than 0.10). It is suggested that carbamazepine is a useful drug for the prophylaxis of manic-depressive illness.

Entities: Chemical Disease Species

Mesh：

Substances：
Carbamazepine

Year: 1981 PMID： 6785799 DOI： 10.1007/BF00431111

Source DB: PubMed Journal: Psychopharmacology (Berl) ISSN： 0033-3158 Impact factor: 4.530

2 in total

1. Comparison of the antimanic efficacy of carbamazepine and chlorpromazine: a double-blind controlled study.

Authors: T Okuma; K Inanaga; S Otsuki; K Sarai; R Takahashi; H Hazama; A Mori; M Watanabe
Journal: Psychopharmacology (Berl) Date: 1979 Impact factor: 4.530

2. Anti-manic and prophylactic effects of carbamazepine (Tegretol) on manic depressive psychosis. A preliminary report.

Authors: T Okuma; A Kishimoto; K Inoue; H Matsumoto; A Ogura
Journal: Folia Psychiatr Neurol Jpn Date: 1973

2 in total

17 in total

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Authors: Konstantinos N Fountoulakis; Lakshmi Yatham; Heinz Grunze; Eduard Vieta; Allan Young; Pierre Blier; Siegfried Kasper; Hans Jurgen Moeller
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Review 3. Efficacy of pharmacotherapy in bipolar disorder: a report by the WPA section on pharmacopsychiatry.

Authors: Konstantinos N Fountoulakis; Siegfried Kasper; Ole Andreassen; Pierre Blier; Ahmed Okasha; Emanuel Severus; Marcio Versiani; Rajiv Tandon; Hans-Jürgen Möller; Eduard Vieta
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A preliminary double-blind study on the efficacy of carbamazepine in prophylaxis of manic-depressive illness.

1. Comparison of the antimanic efficacy of carbamazepine and chlorpromazine: a double-blind controlled study.

2. Anti-manic and prophylactic effects of carbamazepine (Tegretol) on manic depressive psychosis. A preliminary report.

Review 1. Review of pharmacological treatment in mood disorders and future directions for drug development.

Review 2. The International College of Neuro-Psychopharmacology (CINP) Treatment Guidelines for Bipolar Disorder in Adults (CINP-BD-2017), Part 2: Review, Grading of the Evidence, and a Precise Algorithm.

Review 3. Efficacy of pharmacotherapy in bipolar disorder: a report by the WPA section on pharmacopsychiatry.

Review 4. Mitochondrial dysfunction as the molecular basis of bipolar disorder: therapeutic implications.

5. The effects of carbamazepine on two animal models of depression.

Review 6. Pharmacological management of bipolar depression: acute treatment, maintenance, and prophylaxis.

Review 7. The manic syndrome: factors which may predict a patient's response to lithium, carbamazepine and valproate.

Review 8. The use of carbamazepine in the treatment of schizophrenic and schizoaffective psychoses: a review.

9. Anticonvulsant Use in the Treatment of Bipolar Disorder: A Primer for Primary Care Physicians.

10. Effects of acute or chronic carbamazepine on experimentally-induced conflict in the rat.