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Literature DB >> 6785322

Monoclonal antibodies to detect human tumours: an experimental approach.

V Moshakis, R McIlhinney, D Raghavan, A M Neville.

Abstract

The use of monoclonal antibodies which can be raised to antigens of choice offers a selective and specific approach for the detection of tumours both in vivo and at a cellular level in biopsy specimens. We demonstrate that a monoclonal antibody raised to human teratoma will localise in a teratoma, growing as a xenograft in immune-suppressed mice.

Entities: Disease Species

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Year: 1981 PMID： 6785322 PMCID： PMC1146483 DOI： 10.1136/jcp.34.3.314

Source DB: PubMed Journal: J Clin Pathol ISSN： 0021-9746 Impact factor: 3.411

8 in total

1. Continuous cultures of fused cells secreting antibody of predefined specificity.

Authors: G Köhler; C Milstein
Journal: Nature Date: 1975-08-07 Impact factor: 49.962

2. THE PREPARATION OF I-131-LABELLED HUMAN GROWTH HORMONE OF HIGH SPECIFIC RADIOACTIVITY.

Authors: F C GREENWOOD; W M HUNTER; J S GLOVER
Journal: Biochem J Date: 1963-10 Impact factor: 3.857

3. Assessment of biochemical tests to screen for metastases in patients with breast cancer.

Authors: R C Coombes; T J Powles; J C Gazet; A G Nash; H T Ford; A McKinna; A M Neville
Journal: Lancet Date: 1980-02-09 Impact factor: 79.321

4. Radioimmunodetection of cancer with radioactive antibodies to carcinoembryonic antigen.

Authors: D M Goldenberg; E E Kim; F H DeLand; S Bennett; F J Primus
Journal: Cancer Res Date: 1980-08 Impact factor: 12.701

5. Tumor location detected with radioactively labeled monoclonal antibody and external scintigraphy.

Authors: B Ballou; G Levine; T R Hakala; D Solter
Journal: Science Date: 1979-11-16 Impact factor: 47.728

6. Use of radiolabeled antibodies to carcinoembryonic antigen for the detection and localization of diverse cancers by external photoscanning.

Authors: D M Goldenberg; F DeLand; E Kim; S Bennett; F J Primus; J R van Nagell; N Estes; P DeSimone; P Rayburn
Journal: N Engl J Med Date: 1978-06-22 Impact factor: 91.245

7. Localisation of tumour deposits by external scanning after injection of radiolabelled anti-carcinoembryonic antigen.

Authors: P W Dykes; K R Hine; A R Bradwell; J C Blackburn; T A Reeder; Z Drolc; S N Booth
Journal: Br Med J Date: 1980-01-26

8. Potential pathological application of immunocytochemical methods to the detection of micrometastases.

Authors: J P Sloane; M G Ormerod; A M Neville
Journal: Cancer Res Date: 1980-08 Impact factor: 12.701

8 in total

14 in total

1. Advances in pathology and immunocytochemistry.

Authors: E Heyderman
Journal: J R Soc Med Date: 1985 Impact factor: 5.344

2. Stability and in vivo behavior of Rh[16aneS4-diol]211 at complex: a potential precursor for astatine radiopharmaceuticals.

Authors: Marek Pruszyński; Monika Łyczko; Aleksander Bilewicz; Michael R Zalutsky
Journal: Nucl Med Biol Date: 2014-12-23 Impact factor: 2.408

Monoclonal antibodies to detect human tumours: an experimental approach.

1. Continuous cultures of fused cells secreting antibody of predefined specificity.

2. THE PREPARATION OF I-131-LABELLED HUMAN GROWTH HORMONE OF HIGH SPECIFIC RADIOACTIVITY.

3. Assessment of biochemical tests to screen for metastases in patients with breast cancer.

4. Radioimmunodetection of cancer with radioactive antibodies to carcinoembryonic antigen.

5. Tumor location detected with radioactively labeled monoclonal antibody and external scintigraphy.

6. Use of radiolabeled antibodies to carcinoembryonic antigen for the detection and localization of diverse cancers by external photoscanning.

7. Localisation of tumour deposits by external scanning after injection of radiolabelled anti-carcinoembryonic antigen.

8. Potential pathological application of immunocytochemical methods to the detection of micrometastases.

1. Advances in pathology and immunocytochemistry.

2. Stability and in vivo behavior of Rh[16aneS4-diol]211 at complex: a potential precursor for astatine radiopharmaceuticals.

3. Pharmacokinetic study of radiolabeled anti-colorectal carcinoma monoclonal antibodies in tumor-bearing nude mice.

4. Immunodetection of thyroid tumors: role of immuno aggregates.

5. Monoclonal antibodies in oncology.

Review 6. Antitumor monoclonal antibodies for radioimmunodetection of tumors and drug targeting.

7. Expression of HMP/AN2, a melanoma associated antigen, in murine cerebral gliomas: potential for radioimmunotargeting.

8. Tumor labeling in vivo using cyanine-conjugated monoclonal antibodies.

9. Radiolocalisation and imaging of stably HPLAP-transfected MO4 tumours with monoclonal antibodies and fragments.

10. Localization of human breast-carcinoma xenografts using antibodies to carcinoembryonic antigen.